Weill Cornell Medical Center, New York-Presbyterian Hospital, New York, USA.
Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
J Telemed Telecare. 2014 Dec;20(8):460-3. doi: 10.1177/1357633X14555639. Epub 2014 Oct 16.
We assessed the diagnostic accuracy of digital photographs of plain film chest X-rays (CXRs) obtained using a mobile phone. The study was a randomized, non-inferiority trial, in which physical plain film CXRs viewed on a light box were compared with digital photographs of plain film CXRs. CXRs were selected from a database of radiology studies to show common pathologies found in Botswana associated with pneumonia, lung carcinoma, tuberculosis, pneumothorax and interstitial disease, as well as normal findings. The pre-selected diagnoses were subsequently verified by a second radiologist. Seven radiologists were randomized to review 75 plain film CXRs on light boxes before viewing 75 digital photographs, or vice versa. Their responses were considered correct if they matched the pre-defined diagnosis. For both modalities, the correct diagnosis was provided in 79% of cases; for plain film CXRs, the correct diagnosis was provided in 82% of cases and for digital photographs the correct diagnosis was provided in 76% of cases. The difference in diagnostic accuracy was -5.7% (95% CI: -10.8% to -0.5%), which confirmed non-inferiority (P<0.001) for the primary outcome of diagnostic accuracy. A subgroup analysis demonstrated non-inferiority for lung carcinoma and pneumonia images, although non-inferiority was not achieved for pneumothorax, tuberculosis, interstitial disease or normal images. The study demonstrates that digital photographs of CXRs obtained via a mobile phone equipped with a digital camera are non-inferior to plain film CXRs.
我们评估了使用手机获取的普通 X 光胸片(CXR)数字照片的诊断准确性。该研究是一项随机、非劣效性试验,其中比较了在灯箱上查看的物理普通 CXR 与普通 CXR 的数字照片。CXR 是从放射学研究数据库中选择的,以显示与博茨瓦纳的肺炎、肺癌、肺结核、气胸和间质性疾病相关的常见病理学,以及正常发现。预先选择的诊断随后由第二位放射科医生验证。七名放射科医生被随机分配到在灯箱上查看 75 张普通 CXR 之前查看 75 张数字照片,或者反之亦然。如果他们的回答与预定义的诊断相匹配,则被认为是正确的。对于两种模式,正确的诊断率均为 79%;对于普通 CXR,正确的诊断率为 82%,而对于数字照片,正确的诊断率为 76%。诊断准确性的差异为-5.7%(95%CI:-10.8%至-0.5%),证实了主要结局(诊断准确性)的非劣效性(P<0.001)。亚组分析表明,对于肺癌和肺炎图像具有非劣效性,尽管对于气胸、肺结核、间质性疾病或正常图像未达到非劣效性。该研究表明,通过配备数码相机的手机获取的 CXR 数字照片与普通 CXR 一样具有非劣效性。