Guo Yongzhi, Sun Tiansheng, Wang Xiaowei, Li Shaoguang, Liu Zhi
Department of Orthopedics, Beijing Army General Hospital, Beijing, Dongcheng District, China (mainland).
Med Sci Monit. 2014 Oct 17;20:1963-8. doi: 10.12659/MSM.892304.
Hip fracture is common in elderly patients. However, few effective studies had linked cognitive impairment to patient clinical outcome.
A total of 244 elderly hip fracture patients were prospectively followed up for 12 months. At 30 days, 6 months, and 1 year after hip repair surgery, patients and/or primary caregivers were interviewed by phone by trained, blinded interviewers. Functional evaluation, from pre-injury through 1 year after the operation, was assessed using the Barthel Index.
Among 244 patients, 43 were diagnosed as having cognitive impairment (Mini-Mental State Examination score <24). Compared to those without cognitive impairment, the 30-day, 6-month, and 1-year mortalities in the impaired patients were significantly higher than that of the cognitively intact patients. Six months after hip repair surgery, the cognitively intact patients presented significantly higher activities of daily living (ADL) scores than the cognitively impaired patients, and only 38.5% of impaired patients returned to their pre-operation baseline levels afterwards. The ADL scores in the impaired patients were similar to the intact ones at 1 year after the operation.
Although they had a higher risk of mortality in hip fracture, functional gain in the cognitively impaired patients was similar to that in the cognitively intact patients at 1-year follow-up.
髋部骨折在老年患者中很常见。然而,很少有有效的研究将认知障碍与患者的临床结局联系起来。
对244例老年髋部骨折患者进行了为期12个月的前瞻性随访。在髋部修复手术后30天、6个月和1年,由经过培训的盲法访视员通过电话对患者和/或主要照顾者进行访谈。使用巴氏指数评估从受伤前到术后1年的功能状况。
在244例患者中,43例被诊断为有认知障碍(简易精神状态检查表评分<24)。与无认知障碍的患者相比,有认知障碍患者的30天、6个月和1年死亡率显著高于认知功能正常的患者。髋部修复手术后6个月,认知功能正常的患者日常生活活动(ADL)评分显著高于认知障碍患者,且只有38.5%的认知障碍患者术后恢复到术前基线水平。术后1年,认知障碍患者的ADL评分与认知功能正常者相似。
虽然认知障碍患者髋部骨折后的死亡风险较高,但在1年随访中,认知障碍患者的功能恢复与认知功能正常者相似。