Department of Anesthesia, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
School of Public Health, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia.
Biomed Res Int. 2021 Jul 14;2021:9166603. doi: 10.1155/2021/9166603. eCollection 2021.
Preoperative fasting is important to reduce the risk of pulmonary aspiration during anesthesia. The influence of prolonged fasting time on glucose levels during anesthesia in children remains uncertain. Therefore, this study is aimed at assessing preoperative fasting time and its association with hypoglycemia during anesthesia in pediatric patients undergoing elective procedures at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. The research hypothesis of the study is as follows: there is a prolonged preoperative fasting time, and it influences the glucose levels during anesthesia among pediatric patients undergoing elective procedures at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.
Institutional based cross-sectional study was conducted among 258 pediatric patients who had undergone elective procedures in a tertiary care center. A systematic sampling method was used to select study participants. The data were collected through face-to-face interviews and medical record reviews. Binary logistic regression was used to identify associated factors of hypoglycemia during anesthesia among pediatric patients undergoing elective procedures. All explanatory variables with a value of ≤0.25 from the bivariable logistic regression model were fitted into the multivariable logistic regression model to control the possible effect of confounders, and finally, the variables which had an independent association with hypoglycemia were identified based on adjusted odds ratio with 95% confidence interval, and a value less than 0.05 was significant.
The mean (standard deviation) fasting hours from breast milk, solid foods, and clear fluids were 7.75 (2.89), 13.25 (3.14), and 12.31 (3.22), respectively. The majority (89.9%, 57.9%, and 100%) of participants had fasted from solid, breast milk, and clear fluids for more than 8, 6, and 4 hours, respectively. More than one-fourth (26.2%) of participants were hypoglycemic immediately after induction. Residence, order of nothing per mouth, source of patient, and duration of fasting from solid foods had a significant association with hypoglycemia during anesthesia in children.
Children undergoing elective procedures were exposed to unnecessarily long fasting times which were associated with hypoglycemia during anesthesia.
术前禁食对于降低麻醉期间肺部误吸的风险非常重要。长时间禁食对接受择期手术的儿童麻醉期间血糖水平的影响尚不确定。因此，本研究旨在评估术前禁食时间及其与在埃塞俄比亚亚的斯亚贝巴提克里安贝萨专科医院接受择期手术的儿科患者麻醉期间低血糖的关系。研究的假设如下：术前禁食时间延长，且它会影响在埃塞俄比亚亚的斯亚贝巴提克里安贝萨专科医院接受择期手术的儿科患者的麻醉期间血糖水平。
这是一项在埃塞俄比亚亚的斯亚贝巴提克里安贝萨专科医院进行的 258 例接受择期手术的儿科患者的基于机构的横断面研究。采用系统抽样方法选择研究对象。通过面对面访谈和病历回顾收集数据。二项逻辑回归用于确定接受择期手术的儿科患者麻醉期间低血糖的相关因素。从双变量逻辑回归模型中具有 值≤0.25 的所有解释变量被纳入多变量逻辑回归模型，以控制混杂因素的可能影响，最后根据调整后的比值比和 95%置信区间确定与低血糖有独立关联的变量， 值小于 0.05 具有统计学意义。
母乳、固体食物和透明液体的平均（标准差）禁食时间分别为 7.75（2.89）、13.25（3.14）和 12.31（3.22）。大多数（89.9%、57.9%和 100%）参与者禁食固体、母乳和透明液体的时间分别超过 8、6 和 4 小时。超过四分之一（26.2%）的参与者在诱导后立即出现低血糖。居住地、禁食顺序、患者来源和禁食固体食物的时间与儿童麻醉期间的低血糖有显著关联。
接受择期手术的儿童经历了不必要的长时间禁食，这与麻醉期间的低血糖有关。
