结核分枝杆菌3型多重耐药新西兰分离株的基因组序列草图
Draft Genome Sequence of a Multidrug-Resistant New Zealand Isolate of Mycobacterium tuberculosis Lineage 3.
作者信息
Mac Aogáin Micheál, Johari Bushra M, Bower James E, O'Toole Ronan F
机构信息
Department of Clinical Microbiology, School of Medicine, Trinity College Dublin, St. James's Hospital, Dublin, Ireland.
LabPlus, Auckland City Hospital, Auckland, New Zealand.
出版信息
Genome Announc. 2014 Oct 16;2(5):e01017-14. doi: 10.1128/genomeA.01017-14.
Abstract
Multidrug resistance constitutes a threat worldwide to the management of tuberculosis (TB). We report the draft whole-genome sequence of a lineage 3 (East-African Indian) isolate of Mycobacterium tuberculosis which presented as multidrug resistant in New Zealand, and describe a number of single-nucleotide polymorphisms in genes relating to drug resistance.
摘要
多重耐药性对全球结核病的治疗构成威胁。我们报告了一株在新西兰表现为多重耐药的结核分枝杆菌3型（东非-印度型）菌株的全基因组序列草图，并描述了一些与耐药性相关基因中的单核苷酸多态性。
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