塔斯马尼亚首例确诊的多重耐药菌分离株的基因组序列草图
Draft Genome Sequence of the First Confirmed Isolate of Multidrug-Resistant in Tasmania.
作者信息
Gautam Sanjay S, Mac Aogáin Micheál, O'Toole Ronan F
机构信息
School of Medicine, Faculty of Health, University of Tasmania, Hobart, Tasmania, Australia.
Department of Clinical Microbiology, School of Medicine, Trinity College Dublin, St. James's Hospital, Dublin, Ireland.
出版信息
Genome Announc. 2017 Nov 2;5(44):e01230-17. doi: 10.1128/genomeA.01230-17.
Abstract
The spread of multidrug-resistant (MDR) tuberculosis (TB) has become a major global challenge. In 2016, Tasmania recorded its first known incidence of MDR-TB. Here, we report the draft whole-genome sequence of the isolate from this case, TASMDR1, and describe single-nucleotide polymorphisms associated with its drug resistance.
摘要
耐多药结核病（MDR-TB）的传播已成为一项重大的全球挑战。2016年，塔斯马尼亚记录了其首例已知的耐多药结核病发病情况。在此，我们报告了该病例分离株TASMDR1的全基因组序列草图，并描述了与其耐药性相关的单核苷酸多态性。
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