Cui Donghong, Jiang Kaida
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Arch Psychiatry. 2012 Aug;24(4):187-99. doi: 10.3969/j.issn.1002-0829.2012.04.001.
Schizophrenia is a complex disease caused by genetic and environmental factors with a global heritability of more than 80%. By the end of the 1970s, Chinese scientists reported a heritability of schizophrenia of 82.9% in the Chinese Han population. Continuous improvements in research techniques and the recruitment of larger samples have made it possible for Chinese scientists to identify a number of candidate susceptibility genes for schizophrenia. This article reviews the results in genetic research of schizophrenia by Chinese scientists over the last five decades.
精神分裂症是一种由遗传和环境因素引起的复杂疾病，全球遗传度超过80%。到20世纪70年代末，中国科学家报告了中国汉族人群中精神分裂症的遗传度为82.9%。研究技术的不断改进和更大样本量的招募使中国科学家能够识别出一些精神分裂症的候选易感基因。本文综述了中国科学家在过去五十年中精神分裂症遗传研究的成果。
