里德综合征：1型节段性毛发平滑肌瘤与子宫肌瘤。
Reed's syndrome: segmental piloleimyomas type 1 and uterus myomatosus.
作者信息
Wollina Uwe, Schönlebe Jacqueline
机构信息
Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, 01067 Dresden, Germany;
Institute of Pathology "Georg Schmorl", Academic Teaching Hospital Dresden-Friedrichstadt, 01067 Dresden, Germany.
出版信息
J Dermatol Case Rep. 2014 Sep 30;8(3):67-9. doi: 10.3315/jdcr.2014.1178.
BACKGROUND
Cutaneous mosaicism is a possible cause of segmental skin diseases. Cutaneous leiomyomatosis represent a spectrum of conditions ranging from single lesions to disseminated wide distribution. Reed's syndrome, is an autosomal dominant disorder characterized by multiple cutaneous and uterine leiomyomas.
MAIN OBSERVATION
We observed a segmental cutaneous piloleimyomatosis type 1 in a 55-year old female who had an uterus extirpation because of uterine leiomyomas. The cutaneous lesions were moderately painful and localized on her left upper trunk. They presented as firm nodules and small plaques in a linear arrangement. Renal cancer was excluded.
CONCLUSION
In patients with multiple cutaneous (pilo)leiomyomas a search for underlying systemic diseases is necessary in order to not miss benign or malignant tumors of internal organs.
背景
皮肤镶嵌现象是节段性皮肤病的一个可能病因。皮肤平滑肌瘤病涵盖了从单个病损到广泛播散的一系列情况。里德综合征是一种常染色体显性疾病，其特征为多发皮肤和平滑肌瘤。
主要观察结果
我们在一名55岁因子宫肌瘤而切除子宫的女性中观察到1型节段性皮肤毛发平滑肌瘤病。皮肤损害有中度疼痛，位于左上躯干。损害表现为坚实的结节和呈线状排列的小斑块。已排除肾癌。
结论
对于有多发性皮肤（毛发）平滑肌瘤的患者，有必要寻找潜在的全身性疾病，以免漏诊内脏的良性或恶性肿瘤。
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