Basendwh Mohammad A, Fatani Mohammad, Baltow Badee
Department of Dermatology, Qunfudah Medical College, Umm Al-Qura University, Makkah, Saudi Arabia.
Departments of Dermatology, Hera General Hospital, Makkah, Saudi Arabia.
Case Rep Dermatol. 2016 Mar 18;8(1):65-70. doi: 10.1159/000445042. eCollection 2016 Jan-Apr.
Reed's syndrome is an autosomal dominant genetic disorder. Affected individuals are at increased risk of developing benign smooth muscle tumors in the skin and uterus. In this article, we report a case of a 52-year-old female who presented to our dermatology clinic complaining of painful skin lesions on her right arm, left forearm and trunk. The patient had a past medical history of uterine leiomyomatosis for which she underwent hysterectomy 17 years ago. The patient's family history revealed that her mother, 2 sisters and 2 maternal aunts also had uterine leiomyomas. The diagnosis of Reed's syndrome was confirmed by histopathologic examination of the patient's dermal lesion in conjunction with her surgical and family histories. Five years after the initial presentation, the patient underwent treatment with liquid nitrogen cryotherapy for the dermal leiomyomas. After the treatment, marked improvement was noticed with regard to the pain and size of the skin lesions.
里德综合征是一种常染色体显性遗传病。患病个体患皮肤和子宫良性平滑肌瘤的风险增加。在本文中，我们报告了一例52岁女性病例，该患者到我们皮肤科门诊就诊，主诉右臂、左前臂和躯干有疼痛性皮肤损害。患者有子宫平滑肌瘤病史，17年前接受了子宫切除术。患者的家族史显示，她的母亲、2个姐妹和2个姨妈也患有子宫平滑肌瘤。结合患者的手术史和家族史，通过对其皮肤损害进行组织病理学检查，确诊为里德综合征。初次就诊5年后，患者接受了液氮冷冻疗法治疗皮肤平滑肌瘤。治疗后，皮肤损害的疼痛和大小有明显改善。
