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Is there a role for vitamin D in the treatment of chronic pain?

作者信息

Powanda Michael C

机构信息

M/P Biomedical Consultants LLC, 402 Live Oak Drive, Mill Valley, 94941, CA, USA,

出版信息

Inflammopharmacology. 2014 Dec;22(6):327-32. doi: 10.1007/s10787-014-0219-7. Epub 2014 Oct 19.

DOI:10.1007/s10787-014-0219-7
PMID:25326758
Abstract

A brief survey of recent literature was conducted with regard to vitamin D and pain. There is evidence for and against a role for vitamin D in the treatment of chronic pain. The contradictory findings may have to do with study design or perhaps the type and intensity of pain. To answer the question whether there is a role for vitamin D in the treatment of chronic pain, larger and longer duration studies need to be conducted. The design should also be such to assess whether vitamin D might act to increase the effectiveness of existing analgesics and/or reduce the dose and duration of their use, thereby increasing safety.

摘要

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本文引用的文献

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N Engl J Med. 2013 Nov 21;369(21):1991-2000. doi: 10.1056/NEJMoa1306357.
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Plasma vitamin D and biomarkers of cardiometabolic disease risk in adult Canadians, 2007-2009.2007-2009 年加拿大成年人血浆维生素 D 与心血管代谢疾病风险生物标志物。
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Relationship between 25-hydroxyvitamin D and all-cause and cardiovascular disease mortality.
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