Jiang Jue, Huang Lili, Zhang Hongli, Ma Wenqi, Shang Xue, Zhou Qi, Gao Ya, Yu Shanshan, Qi Yanhua
Department of Ultrasound, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, 710004, China.
J Clin Ultrasound. 2015 Mar;43(3):153-6. doi: 10.1002/jcu.22240. Epub 2014 Oct 18.
To investigate the value of contrast-enhanced ultrasound (CEUS) in the differentiation of benign and malignant nodules.
One hundred eighty-nine patients with 213 thyroid nodules were enrolled in this retrospective study. All patients underwent preoperative CEUS and were subsequently scheduled for surgery. The pathology results were obtained after surgery. The time-intensity curves were plotted with TomTec software. The quantitative parameters of the time-intensity curve, such as the maximum intensity of peak (IMAX), the rise time from 10% to 90% of the IMAX, and the time to peak, were compared between the benign and malignant nodules.
There were no significant differences in the rise time or the time to peak among thyroid papillary carcinoma, nodular goiter, and follicular adenoma. However, a significant difference was identified in the IMAX.
A quantitative evaluation of CEUS is helpful to differentiate benign and malignant thyroid nodules.
探讨超声造影(CEUS)在鉴别甲状腺良恶性结节中的价值。
本回顾性研究纳入了189例患有213个甲状腺结节的患者。所有患者术前行CEUS检查,随后安排手术。术后获得病理结果。使用TomTec软件绘制时间-强度曲线。比较了甲状腺良恶性结节时间-强度曲线的定量参数,如峰值最大强度(IMAX)、从IMAX的10%上升至90%的上升时间以及达峰时间。
甲状腺乳头状癌、结节性甲状腺肿和滤泡性腺瘤之间的上升时间或达峰时间无显著差异。然而,在IMAX方面发现了显著差异。
CEUS的定量评估有助于鉴别甲状腺良恶性结节。