Frydrych A M, Slack-Smith L M, Parsons R, Threlfall T
School of Dentistry M512, The University of Western Australia, Perth, Western Australia.
School of Occupational Therapy and Social Work, Curtin University, Perth, Western Australia.
Open Dent J. 2014 Sep 29;8:168-74. doi: 10.2174/1874210601408010168. eCollection 2014.
Squamous cell carcinoma (SCC) is the most common type of malignancy affecting the oral cavity. While exposures to main risk factors for oral SCC such as smoking and alcohol use are higher amongst the Aboriginal people, little is known about oral cancer in this population. This study aimed to describe characteristics and survival of oral SCC in Aboriginal and non-Aboriginal Western Australians.
All primary oral SCC cases reported to the Western Australian Cancer Registry (WACR) between 1990 and 1999 were analysed with respect to person characteristics including: date of birth, sex and indigenous status; and disease characteristics including: date of biopsy, disease stage and site as well as date of recurrence and date of death. Exclusion criteria included diagnosis not based on incisional or excisional biopsy, diagnosis other than oral SCC or a history of another malignant neoplasm.
Aboriginal individuals were more likely to reside in rural areas. No statistically significant differences in oral SCC characteristics and survival were noted between Aboriginal and non-Aboriginal Western Australians.
This study provides new information on person and disease characteristics of Aboriginal Western Australians diagnosed with oral SCC.
鳞状细胞癌（SCC）是影响口腔的最常见恶性肿瘤类型。虽然原住民中接触口腔鳞状细胞癌的主要风险因素如吸烟和饮酒的比例较高，但对该人群的口腔癌了解甚少。本研究旨在描述西澳大利亚原住民和非原住民口腔鳞状细胞癌的特征及生存率。
对1990年至1999年期间向西澳大利亚癌症登记处（WACR）报告的所有原发性口腔鳞状细胞癌病例进行分析，涉及个人特征，包括出生日期、性别和原住民身份；以及疾病特征，包括活检日期、疾病分期和部位以及复发日期和死亡日期。排除标准包括诊断不是基于切开活检或切除活检、非口腔鳞状细胞癌诊断或有其他恶性肿瘤病史。
原住民更有可能居住在农村地区。西澳大利亚原住民和非原住民在口腔鳞状细胞癌特征和生存率方面未发现统计学上的显著差异。
本研究提供了关于被诊断患有口腔鳞状细胞癌的西澳大利亚原住民的个人和疾病特征的新信息。
