Dooley Ian, Treacy Max, O'Rourke Micheal, Khaild Ibrar, Kilmartin Dara
a The Royal Victoria Eye and Ear Hospital , Dublin , Ireland.
Curr Eye Res. 2015;40(10):1073-6. doi: 10.3109/02713683.2014.971936. Epub 2014 Oct 20.
The outer nuclear layer (ONL) contains mostly photoreceptor bodies and reduced post-operative ONL thickness (ONLT) is associated with poor visual outcome in rhegmatogenous retinal detachment (RRD).
Spectral domain ocular coherence tomography was recorded before and 6 weeks following RRD repair in 27 consecutive patients.
The repair consisted of combined 20-guage pars plana vitrectomy (PPV) and encirclement in 66.7% of cases, 22.2% underwent PPV alone and 11.1% scleral buckle alone. The mean (± standard deviation) ONLT was reduced in detached retinae (94.1 ± 31.1 microns) compared to the unaffected eye (119.5 ± 26.8 microns). Postoperatively the ONLT increased to 103.3 (± 32.8) microns. ONLT at presentation in the affected eye is significantly and positively correlated with the final ONLT in the affected eye (Pearson's correlation: r = 0.80, p = 0.029).
The finding that ONLT is reduced in detached retinae carries implications for visual prognosis.
外核层（ONL）主要包含光感受器细胞体，孔源性视网膜脱离（RRD）术后外核层厚度（ONLT）降低与视觉预后不良相关。
对27例连续患者在RRD修复术前及术后6周进行了频域光学相干断层扫描。
66.7%的病例采用20G玻璃体切割联合环扎术进行修复，22.2%的患者仅接受玻璃体切割术，11.1%的患者仅接受巩膜扣带术。与未受影响的眼（119.5±26.8微米）相比，脱离视网膜的平均（±标准差）ONLT降低（94.1±31.1微米）。术后ONLT增加至103.3（±32.8）微米。患眼术前的ONLT与患眼最终的ONLT呈显著正相关（Pearson相关系数：r = 0.80，p = 0.029）。
脱离视网膜中ONLT降低这一发现对视觉预后具有重要意义。
