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复发性孔源性视网膜脱离脉络膜厚度变化分析

Analysis of Choroidal Thickness Changes in Recurrent Rhegmatogenous Retinal Detachment.

作者信息

Chung Gyu Chul, Lee Soo Jung, Pak Kang Yeun

机构信息

Department of Ophthalmology, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.

Lee Eye Clinic, Busan, Korea.

出版信息

Korean J Ophthalmol. 2024 Dec;38(6):489-495. doi: 10.3341/kjo.2024.0051. Epub 2024 Oct 22.

DOI:10.3341/kjo.2024.0051
PMID:39434577
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11647095/
Abstract

PURPOSE

To analyze changes in choroidal thickness in patients with recurrent rhegmatogenous retinal detachment (RRD) before and after surgical intervention and to identify factors that influence changes in choroidal thickness.

METHODS

A retrospective observational study was conducted on patients who underwent surgery for recurrent RRD from November 2019 to March 2023. Choroidal thickness was measured using optical coherence tomography at baseline and at 2 and 6 months postoperatively. The study analyzed the impact of various factors on choroidal thickness changes.

RESULTS

The study included 33 patients, demonstrating a significant decrease in choroidal thickness in the surgical eye compared to the fellow eye over a 6-month period. In the univariate analysis, changes in choroidal thickness were significantly correlated with changes in central retinal thickness (p = 0.048) from baseline to 2 months and with proliferative vitreoretinopathy (PVR) grade from 2 to 6 months (p = 0.009) and from baseline to 6 months (p = 0.020). In the multivariate analysis, an association was found between changes in choroidal thickness from 2 to 6 months and PVR grade (p = 0.030).

CONCLUSIONS

The findings indicate that surgical reattachment in eyes with recurrent RRD leads to a significant reduction in choroidal thickness. The extent of this reduction is influenced by the severity of PVR, highlighting the importance of considering PVR severity when evaluating surgical outcomes in patients with recurrent RRD.

摘要

目的

分析复发性孔源性视网膜脱离(RRD)患者手术干预前后脉络膜厚度的变化,并确定影响脉络膜厚度变化的因素。

方法

对2019年11月至2023年3月接受复发性RRD手术的患者进行回顾性观察研究。使用光学相干断层扫描在基线、术后2个月和6个月测量脉络膜厚度。该研究分析了各种因素对脉络膜厚度变化的影响。

结果

该研究纳入了33例患者,结果显示手术眼的脉络膜厚度在6个月内与对侧眼相比显著降低。在单因素分析中,从基线到2个月,脉络膜厚度的变化与中央视网膜厚度的变化显著相关(p = 0.048),从2个月到6个月以及从基线到6个月,脉络膜厚度的变化与增殖性玻璃体视网膜病变(PVR)分级显著相关(p = 0.009和p = 0.020)。在多因素分析中,发现2个月到6个月脉络膜厚度的变化与PVR分级之间存在关联(p = 0.030)。

结论

研究结果表明,复发性RRD眼的手术复位导致脉络膜厚度显著降低。这种降低的程度受PVR严重程度的影响,突出了在评估复发性RRD患者手术结果时考虑PVR严重程度的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/445f/11647095/4718bdef7ca1/kjo-2024-0051f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/445f/11647095/74b0683ff562/kjo-2024-0051f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/445f/11647095/4718bdef7ca1/kjo-2024-0051f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/445f/11647095/74b0683ff562/kjo-2024-0051f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/445f/11647095/4718bdef7ca1/kjo-2024-0051f2.jpg

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本文引用的文献

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J AAPOS. 2022 Jun;26(3):127.e1-127.e5. doi: 10.1016/j.jaapos.2021.12.011. Epub 2022 May 4.
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The effect of silicone oil tamponade on retinal layers and choroidal thickness in patients with rhegmatogenous retinal detachment: a systematic review and meta-analysis.硅油填塞对孔源性视网膜脱离患者视网膜各层及脉络膜厚度的影响:一项系统评价与荟萃分析。
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Retinal Microvasculature Changes After Repair of Macula-off Retinal Detachment Assessed with Optical Coherence Tomography Angiography.
光学相干断层扫描血管造影评估黄斑脱离视网膜复位术后视网膜微血管变化
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Subfoveal choroidal thickness change following pars plana vitrectomy with silicone oil endotamponade for rhegmatogenous retinal detachment.采用硅油眼内填充的扁平部玻璃体切除术治疗孔源性视网膜脱离后黄斑中心凹下脉络膜厚度的变化
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Effects of Intravitreal Silicone Oil on Subfoveal Choroidal Thickness.玻璃体内硅油对黄斑下脉络膜厚度的影响。
Ophthalmologica. 2018;239(2-3):159-166. doi: 10.1159/000485851. Epub 2018 Jan 25.
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