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运用现代技术分析研究正常眼压性青光眼中角膜厚度与视盘形态之间的相关性。

Correlation between corneal thickness and optic disc morphology in normal tension glaucoma using modern technical analysis.

作者信息

Coman Laurenţiu, Costescu Monica, Alecu Mihail, Coman Oana Andreia

机构信息

Department of Physiology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania;

出版信息

Rom J Morphol Embryol. 2014;55(3):857-62.

PMID:25329112
Abstract

The purpose of this study was to evaluate the relationship between central corneal thickness (CCT) and optic disc morphology in normal tension glaucoma (NTG). Patients with NTG underwent eye examination, optic disc imaging with Heildelberg Retina Tomograph II (HRT II) and ultrasound corneal pachymetry. The morphological parameters of the optic discs were used to classify the eyes into four groups: generalized enlargement (GE) type, myopic glaucomatous (MY) type, focal ischemic (FI) type and senile sclerotic (SS) type. A correlation between CCT and optic disc morphology obtained by HRT II was calculated. Multiple comparison and post hoc tests were performed in order to determine the significance of the differences between the four groups. The strongest correlation was between CCT and the parameters of optic disc imaging obtained at HRT II in the GE type of optic disc.

摘要

本研究的目的是评估正常眼压性青光眼(NTG)患者中央角膜厚度(CCT)与视盘形态之间的关系。NTG患者接受眼部检查、使用海德堡视网膜断层扫描仪II(HRT II)进行视盘成像以及超声角膜测厚。视盘的形态学参数被用于将眼睛分为四组:普遍增大(GE)型、近视性青光眼(MY)型、局灶性缺血(FI)型和老年性硬化(SS)型。计算了CCT与通过HRT II获得的视盘形态之间的相关性。进行了多重比较和事后检验,以确定四组之间差异的显著性。在GE型视盘中,CCT与通过HRT II获得的视盘成像参数之间的相关性最强。

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引用本文的文献

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Major review: Molecular genetics of primary open-angle glaucoma.重大综述:原发性开角型青光眼的分子遗传学
Exp Eye Res. 2017 Jul;160:62-84. doi: 10.1016/j.exer.2017.05.002. Epub 2017 May 10.
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Corneal Segmentation Analysis Increases Glaucoma Diagnostic Ability of Optic Nerve Head Examination, Heidelberg Retina Tomograph's Moorfield's Regression Analysis, and Glaucoma Probability Score.角膜分割分析提高了视神经乳头检查、海德堡视网膜断层扫描的摩尔菲尔德回归分析以及青光眼概率评分对青光眼的诊断能力。
J Ophthalmol. 2015;2015:215951. doi: 10.1155/2015/215951. Epub 2015 May 27.