Omodaka Kazuko, Nakazawa Toru, Otomo Takaaki, Nakamura Masahiko, Fuse Nobuo, Nishida Kohji
Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan.
Clin Ophthalmol. 2010 Jul 30;4:765-72. doi: 10.2147/opth.s9741.
To investigate the correlation between the morphology of the optic disc and the visual function of eyes with open-angle glaucoma (OAG).
One hundred and three eyes of 76 patients with OAG were studied. The baseline optic disc morphology was used to classify the eyes into four types: focal ischemic type (FI), myopic glaucomatous type (MY), senile sclerotic type (SS), and generalized enlargement type (GE). The morphological parameters of the disc were determined by the Heidelberg Retina Tomograph II (HRT-II) and the visual function by the mean deviation (MD) of the Humphrey field analyzer.
Fourteen eyes were classified as the FI type; 52 as the MY type; 17 as the SS type; and 20 as the GE type. The highest correlation coefficients of HRT-II parameters to the MDs was the cup/disc area ratio (r = -0.27) for all groups, the vertical cup/disc ratio (r = -0.42) in the MY group, the maximum cup depth (r = 0.49) in the SS group, and the cup area (r = -0.70) in the GE group. However, none of the parameters was correlated in the FI group.
The correlation between the HRT-II parameters and MDs was different for the four disc types. These findings suggest that a classification of optic disc morphology had a benefit for interpreting the measured values of HRT-II.
研究开角型青光眼（OAG）患者视盘形态与视功能之间的相关性。
对76例OAG患者的103只眼睛进行了研究。根据基线视盘形态将眼睛分为四种类型：局灶缺血型（FI）、近视性青光眼型（MY）、老年性硬化型（SS）和普遍性扩大型（GE）。视盘的形态学参数由海德堡视网膜断层扫描仪II（HRT-II）测定，视功能由 Humphrey 视野分析仪的平均偏差（MD）测定。
14只眼睛被分类为FI型；52只为MY型；17只为SS型；20只为GE型。所有组中，HRT-II参数与MD的最高相关系数为杯盘面积比（r = -0.27），MY组为垂直杯盘比（r = -0.42），SS组为最大杯深（r = 0.49），GE组为杯面积（r = -0.70）。然而，FI组中没有参数具有相关性。
四种视盘类型中，HRT-II参数与MD之间的相关性有所不同。这些发现表明，视盘形态分类有助于解释HRT-II的测量值。
