Cahill P L, Kuhajek J M
a Coastal & Freshwater Group , Cawthron Institute , Nelson , New Zealand.
Biofouling. 2014 Oct;30(9):1035-43. doi: 10.1080/08927014.2014.966305.
Ongoing investigation of the candidate antifouling (AF) biocide polygodial (PG) has revealed that this compound may be contact active, whereby it can confer effect while remaining bound within a stable matrix. To test this hypothesis, the AF activity of PG-laced coatings was compared to that of seawater in which PG-laced coatings had been soaked. Four coating types spanning high to low affinity for PG were examined and AF activity was assessed based on inhibition of settlement and metamorphosis of larvae of three fouling organisms: Ciona savignyi Herdman, Mytilus galloprovincialis Lamarck and Spirobranchus caraniferus Gray. Direct exposure to the coatings had a significantly greater impact on larval metamorphosis than indirect exposure to seawater in which the coatings had been soaked. In particular, metamorphosis was almost completely inhibited by high-affinity coatings containing ≥ 200 ng of PG per replicate, while corresponding soaking waters had no detectable effect. These findings support the assertion that PG is contact active.
对候选防污（AF）杀生剂多香木萜（PG）的持续研究表明，该化合物可能具有接触活性，即它在结合于稳定基质内时仍能发挥作用。为验证这一假设，将含有PG的涂层的AF活性与浸泡过含有PG涂层的海水的AF活性进行了比较。研究了四种对PG亲和力从高到低的涂层类型，并基于对三种污损生物幼虫（萨氏海鞘、地中海贻贝和加勒比螺旋苔藓虫）附着和变态的抑制作用来评估AF活性。直接接触涂层对幼虫变态的影响显著大于间接接触浸泡过涂层的海水。特别是，每重复样本中含有≥200 ng PG的高亲和力涂层几乎完全抑制了变态，而相应的浸泡水则没有可检测到的效果。这些发现支持了PG具有接触活性的论断。
