Evanoff Anastasia, Sabbath Erika L, Carton Matthieu, Czernichow Sebastien, Zins Marie, Leclerc Annette, Descatha Alexis
Univ Versailles St-Quentin, Versailles, France; UMS 011 Population-based Epidemiologic Cohorts Unit Inserm, Villejuif, France; Harvard College, Cambridge, MA, United States of America.
Harvard Center for Population and Development Studies, Cambridge, MA, United States of America.
PLoS One. 2014 Oct 17;9(10):e109633. doi: 10.1371/journal.pone.0109633. eCollection 2014.
To analyze relationships between physical occupational exposures, post-retirement shoulder/knee pain, and obesity.
9 415 male participants (aged 63-73 in 2012) from the French GAZEL cohort answered self-administered questionnaires in 2006 and 2012. Occupational exposures retrospectively assessed in 2006 included arm elevation and squatting (never, <10 years, ≥10 years). "Severe" shoulder and knee pain were defined as ≥5 on an 8-point scale. BMI was self-reported.
Mean BMI was 26.59 kg/m2 +/-3.5 in 2012. Long-term occupational exposure to arm elevation and squatting predicted severe shoulder and knee pain after retirement. Obesity (BMI≥30 kg/m2) was a risk factor for severe shoulder pain (adjusted OR 1.28; 95% CI 1.03, 1.90). Overweight (adjusted OR 1.71; 1.28,2.29) and obesity (adjusted OR 3.21; 1.90,5.41) were risk factors for severe knee pain. In stratified models, associations between long-term squatting and severe knee pain varied by BMI.
Obesity plays a role in relationships between occupational exposures and musculoskeletal pain. Further prospective studies should use BMI in analyses of musculoskeletal pain and occupational factors, and continue to clarify this relationship.
分析职业身体暴露、退休后肩/膝关节疼痛与肥胖之间的关系。
来自法国GAZEL队列的9415名男性参与者（2012年年龄为63 - 73岁）在2006年和2012年回答了自填式问卷。2006年回顾性评估的职业暴露包括手臂抬高和下蹲（从不、<10年、≥10年）。“严重”的肩痛和膝关节疼痛定义为在8分制量表上≥5分。体重指数（BMI）为自我报告。
2012年平均BMI为26.59kg/m²±3.5。长期职业性手臂抬高和下蹲暴露预示着退休后严重的肩痛和膝关节疼痛。肥胖（BMI≥30kg/m²）是严重肩痛的一个危险因素（调整后的比值比为1.28；95%置信区间为1.03，1.90）。超重（调整后的比值比为1.71；1.28，2.29）和肥胖（调整后的比值比为3.21；1.90，5.41）是严重膝关节疼痛的危险因素。在分层模型中，长期下蹲与严重膝关节疼痛之间的关联因BMI而异。
肥胖在职业暴露与肌肉骨骼疼痛的关系中起作用。进一步的前瞻性研究应在分析肌肉骨骼疼痛和职业因素时使用BMI，并继续阐明这种关系。
