输卵管中卵巢癌的前驱病变：浆液性输卵管上皮内癌——最新进展
Precursors of ovarian cancer in the fallopian tube: serous tubal intraepithelial carcinoma--an update.
作者信息
Zeppernick Felix, Meinhold-Heerlein Ivo, Shih Ie-Ming
机构信息
Departments of Pathology and Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA; Department of Gynecology and Obstetrics, University Hospital Aachen, Aachen, Germany.
出版信息
J Obstet Gynaecol Res. 2015 Jan;41(1):6-11. doi: 10.1111/jog.12550. Epub 2014 Oct 20.
Abstract
Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of 'serous tubal intraepithelial carcinoma', which is believed to represent the precursor lesion in high-grade serous ovarian carcinoma. In this review, lines of evidence for this are discussed and possible future implications for clinical and research settings are outlined.
摘要
卵巢肿瘤包含多种类型。其中最大的一类，即上皮性卵巢癌，可分为两个主要类型，I型和II型肿瘤。近年来对卵巢癌发生发展的认识取得了进展，发现了“浆液性输卵管上皮内癌”，它被认为是高级别浆液性卵巢癌的前驱病变。在这篇综述中，将讨论支持这一观点的证据，并概述其对临床和研究领域未来可能产生的影响。
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