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Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium.阿司匹林、非阿司匹林非甾体抗炎药和对乙酰氨基酚的使用与侵袭性上皮性卵巢癌风险：卵巢癌协会联盟的 pooled 分析。
J Natl Cancer Inst. 2014 Feb;106(2):djt431. doi: 10.1093/jnci/djt431.
2
Outcome of unexpected adnexal neoplasia discovered during risk reduction salpingo-oophorectomy in women with germ-line BRCA1 or BRCA2 mutations.BRCA1 或 BRCA2 基因突变携带者行预防性输卵管-卵巢切除术时偶然发现附件区肿瘤的结局。
Gynecol Oncol. 2014 Feb;132(2):280-6. doi: 10.1016/j.ygyno.2013.12.009. Epub 2013 Dec 12.
3
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.Brca;Tp53;Pten 模型中，输卵管分泌上皮的转化导致高级别浆液性卵巢癌。
Cancer Cell. 2013 Dec 9;24(6):751-65. doi: 10.1016/j.ccr.2013.10.013.
4
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5
Clinical outcome of isolated serous tubal intraepithelial carcinomas (STIC).孤立性输卵管上皮内浆液性癌（STIC）的临床转归。
Int J Gynecol Cancer. 2013 Nov;23(9):1603-11. doi: 10.1097/IGC.0b013e3182a80ac8.
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Through the glass darkly: intraepithelial neoplasia, top-down differentiation, and the road to ovarian cancer.雾里看花：上皮内瘤变、自上而下的分化，以及通向卵巢癌的道路。
J Pathol. 2013 Dec;231(4):402-12. doi: 10.1002/path.4263.
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Short-term effects of salpingectomy during laparoscopic hysterectomy on ovarian reserve: a pilot randomized controlled trial.腹腔镜子宫切除术中输卵管切除术对卵巢储备功能的短期影响：一项初步随机对照试验。
Fertil Steril. 2013 Dec;100(6):1704-8. doi: 10.1016/j.fertnstert.2013.07.1997. Epub 2013 Aug 29.
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Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: primum non nocere.预防性输卵管切除术在绝经前低危女性中的卵巢癌预防作用：首要原则是不造成伤害。
Gynecol Oncol. 2013 Jun;129(3):448-51. doi: 10.1016/j.ygyno.2013.03.023. Epub 2013 Apr 2.
9
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10
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Int J Gynecol Cancer. 2012 Oct;22(8):1310-5. doi: 10.1097/IGC.0b013e31826b5dcc.

输卵管中卵巢癌的前驱病变：浆液性输卵管上皮内癌——最新进展

Precursors of ovarian cancer in the fallopian tube: serous tubal intraepithelial carcinoma--an update.

作者信息

Zeppernick Felix, Meinhold-Heerlein Ivo, Shih Ie-Ming

机构信息

Departments of Pathology and Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA; Department of Gynecology and Obstetrics, University Hospital Aachen, Aachen, Germany.

出版信息

J Obstet Gynaecol Res. 2015 Jan;41(1):6-11. doi: 10.1111/jog.12550. Epub 2014 Oct 20.

DOI:10.1111/jog.12550
PMID:25330822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4352308/
Abstract

Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of 'serous tubal intraepithelial carcinoma', which is believed to represent the precursor lesion in high-grade serous ovarian carcinoma. In this review, lines of evidence for this are discussed and possible future implications for clinical and research settings are outlined.

摘要

卵巢肿瘤包含多种类型。其中最大的一类，即上皮性卵巢癌，可分为两个主要类型，I型和II型肿瘤。近年来对卵巢癌发生发展的认识取得了进展，发现了“浆液性输卵管上皮内癌”，它被认为是高级别浆液性卵巢癌的前驱病变。在这篇综述中，将讨论支持这一观点的证据，并概述其对临床和研究领域未来可能产生的影响。