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戈舍瑞林治疗绝经前转移性乳腺癌患者

Zoladex in the treatment of premenopausal metastatic breast cancer patients.

作者信息

Kaufmann M

机构信息

Universitats-Frauenklinik, Heidelberg, FRG.

出版信息

Horm Res. 1989;32 Suppl 1:202-5. doi: 10.1159/000181346.

DOI:10.1159/000181346
PMID:2533150
Abstract

In an open phase II, multicentre study with 118 pre- or perimenopausal women with histologically proven advanced breast cancer, Zoladex depot (3.6 mg) has been shown to produce an effective castration and response rates, which are comparable to those from oophorectomy.

摘要

在一项开放的II期多中心研究中，对118名组织学确诊为晚期乳腺癌的绝经前或围绝经期女性进行了研究，结果显示，戈舍瑞林长效注射剂（3.6毫克）可产生有效的去势效果和反应率，与卵巢切除术的效果相当。

相似文献

1
Zoladex in the treatment of premenopausal metastatic breast cancer patients.戈舍瑞林治疗绝经前转移性乳腺癌患者
Horm Res. 1989;32 Suppl 1:202-5. doi: 10.1159/000181346.
2
Goserelin, a depot gonadotrophin-releasing hormone agonist in the treatment of premenopausal patients with metastatic breast cancer. German Zoladex Trial Group.戈舍瑞林，一种长效促性腺激素释放激素激动剂，用于治疗绝经前转移性乳腺癌患者。德国诺雷德试验组。
J Clin Oncol. 1989 Aug;7(8):1113-9. doi: 10.1200/JCO.1989.7.8.1113.
3
A multi-centre randomised study to compare the effects of ovarian ablation with Zoladex depot in pre- and perimenopausal patients with advanced breast cancer.一项多中心随机研究，比较戈舍瑞林长效注射剂卵巢去势对绝经前和围绝经期晚期乳腺癌患者的疗效。
Horm Res. 1989;32 Suppl 1:218-20. doi: 10.1159/000181350.
4
Zoladex in advanced breast cancer.
Horm Res. 1989;32 Suppl 1:206-8. doi: 10.1159/000181347.
5
The depot GnRH analogue goserelin in the treatment of premenopausal patients with metastatic breast cancer--a 5-year experience and further endocrine therapies. Cooperative German Zoladex Study Group.长效促性腺激素释放激素类似物戈舍瑞林治疗绝经前转移性乳腺癌患者——5年经验及进一步内分泌治疗。德国诺雷德协作研究组
Onkologie. 1991 Feb;14(1):22-4, 26-8, 30. doi: 10.1159/000216940.
6
The use of an LH-RH agonist (ICI 118630, Zoladex) in advanced premenopausal breast cancer.促黄体生成素释放激素激动剂（ICI 118630，诺雷德）在绝经前晚期乳腺癌中的应用。
Br J Cancer. 1986 May;53(5):629-36. doi: 10.1038/bjc.1986.106.
7
Endocrinology of Zoladex in postmenopausal women.戈舍瑞林在绝经后女性中的内分泌学
Horm Res. 1989;32 Suppl 1:209-12. doi: 10.1159/000181348.
8
Goserelin--depot preparation of LHRH analogue used in the treatment of endometriosis.戈舍瑞林——一种用于治疗子宫内膜异位症的促性腺激素释放激素（LHRH）类似物长效制剂。
Prog Clin Biol Res. 1990;323:383-92.
9
LH-RH analogue Zoladex in the treatment of pre- and perimenopausal women with metastatic breast cancer (results of the Italian Cooperative Study).
Eur J Gynaecol Oncol. 1991;12(6):429-37.
10
A phase III open randomized study of Zoladex 3.6 mg depot vs. DES 3 mg per day in untreated advanced prostate cancer: a West Midlands Urological Research Group Study.一项关于戈舍瑞林3.6毫克长效注射剂与己烯雌酚每日3毫克治疗未经治疗的晚期前列腺癌的III期开放随机研究：西米德兰兹泌尿外科研究小组研究
Prog Clin Biol Res. 1989;303:47-52.

引用本文的文献

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Complete estrogen blockade for the treatment of metastatic and early stage breast cancer.完全雌激素阻断用于治疗转移性和早期乳腺癌。
Drugs Aging. 2000 Apr;16(4):261-71. doi: 10.2165/00002512-200016040-00002.
2
GnRH receptors in human breast cancer and its contiguous not-involved breast tissue.人乳腺癌及其相邻未受累乳腺组织中的促性腺激素释放激素受体
J Endocrinol Invest. 2000 Feb;23(2):90-6. doi: 10.1007/BF03343685.
3
Characterization of binding sites for a GnRH-agonist (buserelin) in human breast cancer biopsies and their distribution in relation to tumor parameters.
人乳腺癌活检中促性腺激素释放激素激动剂（布舍瑞林）结合位点的特征及其与肿瘤参数相关的分布情况。
Breast Cancer Res Treat. 1993;25(1):37-46. doi: 10.1007/BF00662399.
4
Inhibition of growth of MCF-7 MIII human breast carcinoma in nude mice by treatment with agonists or antagonists of LH-RH.
Breast Cancer Res Treat. 1992;21(1):35-45. doi: 10.1007/BF01811962.
5
Overview of new treatments for breast cancer.乳腺癌新疗法概述
Breast Cancer Res Treat. 1992;21(1):3-13. doi: 10.1007/BF01811959.