一个问题两个方面！主动脉瓣狭窄中的左心室收缩和舒张功能障碍。
One problem two issues! Left ventricular systolic and diastolic dysfunction in aortic stenosis.
机构信息
1 Division of Cardiothoracic Surgery, Department of Surgery, Texas A & M Health Science Center at Scott & White Memorial Hospital, Temple, TX, USA ; 2 Division of Cardiothoracic Surgery, Prince of Wales & Sydney Children's Hospital, Barker Street, Randwick, Sydney, NSW, Australia ; 3 Liverpool Heart and Chest Hospital, NHS Foundation Trust, Liverpool, UK.
出版信息
Ann Transl Med. 2014 Jan;2(1):10. doi: 10.3978/j.issn.2305-5839.2013.06.05.
Abstract
Reports suggested that immediate post-aortic valve replacement (AVR); left ventricular (LV) dysfunction may be an important risk for morbidity and mortality in patients requiring positive inotropic support. Several factors have been identified as significant prognostic factors i.e., LV systolic dysfunction, LV diastolic dysfunction (LV-DD), heart failure and myocardial infarction (MI). Specific to pathophysiological changes associated with AS, markers of systolic LV function (e.g., LVEF) have been extensively studied in management, yet only a few studies have analysed the association between LV-DD and immediate post-operative LV dysfunction This review brings together the current body of evidence on this issue.
摘要
报告表明，主动脉瓣置换术后（AVR）即刻左心室（LV）功能障碍可能是需要正性肌力支持的患者发病率和死亡率的重要危险因素。已经确定了几个重要的预后因素，例如 LV 收缩功能障碍、LV 舒张功能障碍（LV-DD）、心力衰竭和心肌梗死（MI）。具体到与 AS 相关的病理生理变化，LV 收缩功能的标志物（例如，LVEF）在管理中已得到广泛研究，但只有少数研究分析了 LV-DD 与术后即刻 LV 功能障碍之间的关系。本综述汇集了关于这一问题的现有证据。
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