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One problem two issues! Left ventricular systolic and diastolic dysfunction in aortic stenosis.一个问题两个方面！主动脉瓣狭窄中的左心室收缩和舒张功能障碍。
Ann Transl Med. 2014 Jan;2(1):10. doi: 10.3978/j.issn.2305-5839.2013.06.05.
2
Clinical aspects of left ventricular diastolic function assessed by Doppler echocardiography following acute myocardial infarction.急性心肌梗死后经多普勒超声心动图评估左心室舒张功能的临床方面
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Preoperative diastolic function predicts the onset of left ventricular dysfunction following aortic valve replacement in high-risk patients with aortic stenosis.术前舒张功能可预测高危主动脉瓣狭窄患者主动脉瓣置换术后左心室功能障碍的发生。
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Left ventricular remodeling early after aortic valve replacement: differential effects on diastolic function in aortic valve stenosis and aortic regurgitation.主动脉瓣置换术后早期左心室重构：对主动脉瓣狭窄和主动脉瓣反流舒张功能的不同影响。
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Continuing dilemmas concerning aortic valve replacement in patients with advanced left ventricular systolic dysfunction.晚期左心室收缩功能障碍患者主动脉瓣置换术持续存在的困境。
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The clinical value and safety of ECG-gated dipyridamole myocardial perfusion imaging in patients with aortic stenosis.心电图门控双嘧达莫心肌灌注显像在主动脉瓣狭窄患者中的临床价值和安全性。
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本文引用的文献

1
Ventricular hypertrophy and left atrial dilatation persist and are associated with reduced survival after valve replacement for aortic stenosis.主动脉瓣狭窄置换术后，心室肥厚和左心房扩张持续存在，并与生存率降低相关。
J Thorac Cardiovasc Surg. 2014 Jan;147(1):362-369.e8. doi: 10.1016/j.jtcvs.2012.12.016. Epub 2013 Jan 11.
2
A practical approach to echocardiographic assessment of perioperative diastolic dysfunction.超声心动图评估围术期舒张功能障碍的实用方法。
J Cardiothorac Vasc Anesth. 2012 Dec;26(6):1115-23. doi: 10.1053/j.jvca.2012.07.012.
3
Prognostic value of myocardial fibrosis in patients with severe aortic valve stenosis.心肌纤维化对严重主动脉瓣狭窄患者的预后价值。
J Thorac Cardiovasc Surg. 2012 Oct;144(4):830-7. doi: 10.1016/j.jtcvs.2011.11.024. Epub 2012 Jan 12.
4
Levosimendan versus an intra-aortic balloon pump in adult cardiac surgery patients with low cardiac output.左西孟旦与主动脉内球囊反搏在低心输出量成年心脏手术患者中的应用比较
J Cardiothorac Vasc Anesth. 2011 Dec;25(6):1154-62. doi: 10.1053/j.jvca.2011.01.001. Epub 2011 Mar 3.
5
Outcome of patients with low-gradient "severe" aortic stenosis and preserved ejection fraction.低梯度“重度”主动脉瓣狭窄伴射血分数保留患者的结局。
Circulation. 2011 Mar 1;123(8):887-95. doi: 10.1161/CIRCULATIONAHA.110.983510. Epub 2011 Feb 14.
6
Aortic stenosis: An update.主动脉瓣狭窄：最新进展
World J Cardiol. 2010 Jun 26;2(6):135-9. doi: 10.4330/wjc.v2.i6.135.
7
Effect of bisphosphonates on the progression of degenerative aortic stenosis.双膦酸盐对退行性主动脉瓣狭窄进展的影响。
Echocardiography. 2011 Jan;28(1):1-7. doi: 10.1111/j.1540-8175.2010.01256.x.
8
Preoperative diastolic function predicts the onset of left ventricular dysfunction following aortic valve replacement in high-risk patients with aortic stenosis.术前舒张功能可预测高危主动脉瓣狭窄患者主动脉瓣置换术后左心室功能障碍的发生。
Crit Care. 2010;14(3):R101. doi: 10.1186/cc9040. Epub 2010 Jun 3.
9
Contemporary perioperative results of isolated aortic valve replacement for aortic stenosis.单纯主动脉瓣置换术治疗主动脉瓣狭窄的当代围手术期结果。
Ann Thorac Surg. 2010 Mar;89(3):751-6. doi: 10.1016/j.athoracsur.2009.11.024.
10
Effect of Lipid lowering with rosuvastatin on progression of aortic stenosis: results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trial.瑞舒伐他汀降脂治疗对主动脉瓣狭窄进展的影响：主动脉瓣狭窄进展观察研究的结果：评价瑞舒伐他汀的效果（ASTROMER）试验。
Circulation. 2010 Jan 19;121(2):306-14. doi: 10.1161/CIRCULATIONAHA.109.900027. Epub 2010 Jan 4.

一个问题两个方面！主动脉瓣狭窄中的左心室收缩和舒张功能障碍。

One problem two issues! Left ventricular systolic and diastolic dysfunction in aortic stenosis.

机构信息

1 Division of Cardiothoracic Surgery, Department of Surgery, Texas A & M Health Science Center at Scott & White Memorial Hospital, Temple, TX, USA ; 2 Division of Cardiothoracic Surgery, Prince of Wales & Sydney Children's Hospital, Barker Street, Randwick, Sydney, NSW, Australia ; 3 Liverpool Heart and Chest Hospital, NHS Foundation Trust, Liverpool, UK.

出版信息

Ann Transl Med. 2014 Jan;2(1):10. doi: 10.3978/j.issn.2305-5839.2013.06.05.

DOI:10.3978/j.issn.2305-5839.2013.06.05
PMID:25332986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4200657/
Abstract

Reports suggested that immediate post-aortic valve replacement (AVR); left ventricular (LV) dysfunction may be an important risk for morbidity and mortality in patients requiring positive inotropic support. Several factors have been identified as significant prognostic factors i.e., LV systolic dysfunction, LV diastolic dysfunction (LV-DD), heart failure and myocardial infarction (MI). Specific to pathophysiological changes associated with AS, markers of systolic LV function (e.g., LVEF) have been extensively studied in management, yet only a few studies have analysed the association between LV-DD and immediate post-operative LV dysfunction This review brings together the current body of evidence on this issue.

摘要

报告表明，主动脉瓣置换术后（AVR）即刻左心室（LV）功能障碍可能是需要正性肌力支持的患者发病率和死亡率的重要危险因素。已经确定了几个重要的预后因素，例如 LV 收缩功能障碍、LV 舒张功能障碍（LV-DD）、心力衰竭和心肌梗死（MI）。具体到与 AS 相关的病理生理变化，LV 收缩功能的标志物（例如，LVEF）在管理中已得到广泛研究，但只有少数研究分析了 LV-DD 与术后即刻 LV 功能障碍之间的关系。本综述汇集了关于这一问题的现有证据。