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面部皮肤问题与视觉显示设备工作。流行病学、临床及组织病理学研究。

Facial skin complaints and work at visual display units. Epidemiological, clinical and histopathological studies.

作者信息

Berg M

机构信息

Department of Dermatology, Karolinska Hospital, Stockholm, Sweden.

出版信息

Acta Derm Venereol Suppl (Stockh). 1989;150:1-40.

PMID:2533443
Abstract

Only in Sweden is skin disease reputedly caused by working at visual display units (VDUs) a considerable problem. In the present work facial skin complaints in VDU-exposed persons have been studied by means of epidemiological, clinical and histopathological methods. The results can be summarized as follows. Half the patients referred for dermatological examination because of facial skin complaints they attributed to working at VDUs had rosacea. Most of them claimed that they had pronounced symptoms, but their skin lesions were mild. When they were followed up most of the patients reported improvement without pharmacological therapy in spite of continued VDU work. Individuals exposed to VDUs had significantly more self-reported skin complaints than a nonexposed control population of office employees, but no more visible signs. Skin tumours with malignant potential and unilateral facial skin signs were found in the same frequencies in both categories. Rosacea was the most common facial skin condition (10%) in the 809 randomly selected office employees (mean age 43 years) examined, and this condition as well as the occurrence of telangiectases (found in 57% of the examined population) was no more common among the exposed persons. The answers in the self-administered questionnaires (n = 3745), used when studying the office employees, corresponded poorly to skin status (only 46% correlated), but were reasonably accurate as regards the occurrence of more clear-cut symptoms, such as in atopic or seborrhoeic dermatitis. Patients with skin complaints they said were associated with VDUs had no characteristic histological changes in facial skin. Histological changes of varying degree were also common among the control subjects without skin complaints or exposure to VDUs. This is particularly true of the degree of degenerative change in elastic fibers, which increased with age. Rosacea was more common in women, and there was a strong association between rosacea and migraine, as well as between migraine and patients with symptoms thought to be related to work at VDUs. In contrast to previous assumptions, most subjects with rosacea in this study experienced no impairment due to exposure to sunlight. This work shows that people exposed to VDUs had subjective skin symptoms more often than a nonexposed control population. The design of the study does not permit an analysis of the cause of this phenomenon. The occurrence of skin signs in persons exposed to VDUs is, however, fortuitous from an epidemiological viewpoint.

摘要

据说只有在瑞典,因在视觉显示终端(VDU)工作而引发的皮肤病才是一个相当严重的问题。在本研究中,我们采用流行病学、临床和组织病理学方法,对接触VDU的人员面部皮肤问题进行了研究。结果总结如下:因面部皮肤问题前来皮肤科就诊的患者中,有一半将其归因于VDU工作,而这些患者中半数患有酒渣鼻。他们中的大多数人称症状明显,但皮肤病变却很轻微。随访发现,尽管继续从事VDU工作,但大多数患者在未接受药物治疗的情况下病情有所改善。与未接触VDU的办公室职员对照组相比,接触VDU的个体自我报告的皮肤问题明显更多,但可见体征却没有更多。在这两类人群中,具有恶性潜能的皮肤肿瘤和单侧面部皮肤体征的出现频率相同。在随机抽取的809名办公室职员(平均年龄43岁)中,酒渣鼻是最常见的面部皮肤疾病(10%),在接触VDU的人群中,这种疾病以及毛细血管扩张(在57%的受检人群中发现)并不比未接触者更常见。在研究办公室职员时使用的自填式问卷(n = 3745)中的答案与皮肤状况的对应性较差(只有46%相关),但对于更明确的症状,如特应性皮炎或脂溢性皮炎的发生情况,回答相当准确。那些称皮肤问题与VDU工作有关的患者,面部皮肤没有特征性的组织学变化。在没有皮肤问题或未接触VDU的对照组中,也普遍存在不同程度的组织学变化。弹性纤维的退行性变化程度尤其如此,它会随着年龄的增长而增加。酒渣鼻在女性中更为常见,酒渣鼻与偏头痛之间、偏头痛与那些认为症状与VDU工作有关的患者之间都存在很强的关联。与之前的假设相反,在本研究中,大多数患有酒渣鼻的受试者并未因阳光照射而受到损害。这项研究表明接触VDU的人主观皮肤症状比未接触的对照组更常见。该研究的设计不允许对这一现象的原因进行分析。然而,从流行病学角度来看,接触VDU的人出现皮肤体征是偶然的。

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