Berg M, Lidén S
Department of Dermatology, Karolinska Sjukhuset, Stockholm, Sweden.
Acta Derm Venereol. 1989;69(5):419-23.
In a non-selected population of 809 office employees (454 women and 355 men) 81 persons were diagnosed as having rosacea, giving a prevalence of 10% (women 14%, men 5%). The rosacea group was compared with the rest of the study population. Most of the cases were rather mild. The rosacea was of an erythematotelangiectatic type in 81% of the cases and of a papulopustular type in 19%. Unilateral lesions were found in 11 subjects (14%). Only 17% of those with rosacea were impaired by sunlight, whereas 26% improved. In the rosacea group, 27% were found to suffer from migraine and 42% from a tendency to flush, compared with 13% (p less than 0.001) and 16% (p less than 0.001) respectively in the comparison group. Flushing and the regulatory mechanism of the blood vessels thus seem to be of importance in the pathogenesis of rosacea. Individuals with good pigmentation ability showed a tendency to a decreased occurrence of rosacea. The frequency of eye complaints was the same in the two groups.
在一个由809名办公室职员（454名女性和355名男性）组成的非选择性人群中，81人被诊断患有酒渣鼻，患病率为10%（女性为14%，男性为5%）。将酒渣鼻组与研究人群中的其他人员进行比较。大多数病例相当轻微。81%的病例为红斑毛细血管扩张型酒渣鼻，19%为丘疹脓疱型。11名受试者（14%）发现有单侧损害。酒渣鼻患者中只有17%受到阳光影响，而26%的患者病情有所改善。在酒渣鼻组中，发现27%的人患有偏头痛，42%的人有脸红倾向，而在对照组中分别为13%（p<0.001）和16%（p<0.001）。因此，脸红和血管调节机制在酒渣鼻的发病机制中似乎很重要。色素沉着能力良好的个体患酒渣鼻的发生率有降低的趋势。两组眼部不适的频率相同。
