Citrome Leslie
Dr. Citrome is Clinical Professor of Psychiatry and Behavioral Sciences at New York Medical College in Valhalla, New York, and is the Editor-in-Chief for the International Journal of Clinical Practice, published by Wiley-Blackwell. He is also a member of the World Association of Medical Editors, the International Society for Medical Publication Professionals, and a participant in the Medical Publishing Insights and Practices initiative.
Innov Clin Neurosci. 2014 Jul;11(7-8):42-6.
Clinical trial results have been traditionally communicated through the publication of scholarly reports and reviews in biomedical journals. However, this dissemination of information can be delayed or incomplete, making it difficult to appraise new treatments, or in the case of missing data, evaluate older interventions. Going beyond the routine search of PubMed, it is possible to discover additional information in the "grey literature." Examples of the grey literature include clinical trial registries, patent databases, company and industrywide repositories, regulatory agency digital archives, abstracts of paper and poster presentations on meeting/congress websites, industry investor reports and press releases, and institutional and personal websites.
传统上,临床试验结果是通过在生物医学期刊上发表学术报告和综述来传达的。然而,这种信息传播可能会延迟或不完整,从而难以评估新的治疗方法,或者在数据缺失的情况下,难以评估旧的干预措施。除了常规搜索PubMed之外,还可以在“灰色文献”中发现更多信息。灰色文献的例子包括临床试验注册库、专利数据库、公司和行业范围内的知识库、监管机构数字档案、会议/大会网站上的论文和海报展示摘要、行业投资者报告和新闻稿,以及机构和个人网站。