Chhonker Devender, Faridi M M A, Narang Manish, Sharma S B
Department of Pediatrics, University College of Medical Sciences & Guru Teg Bahadur Hospital, 110095, Shahdara, Delhi, India.
Indian J Pediatr. 2015 Apr;82(4):345-8. doi: 10.1007/s12098-014-1580-7. Epub 2014 Oct 23.
To compare the lipid profile of exclusively breastfed and mixed-fed, term, appropriate for gestation age infants from 6 mo to 1 y of age.
This prospective comparative study included one hundred ninety nine consecutive term healthy infants; 105 on exclusive breastfeeding (EBF) and 94 receiving mixed feeding (MF). These children were recruited at 6 mo of age and followed till 1 y of age. Serum lipid levels of babies were determined at recruitment (6 mo), 9 mo and 1 y of age. Statistical analysis was carried out using SPSS software.
The mean total cholesterol (TC) at 6 mo in exclusively breastfed group (156.38 ± 50.42 mg/dl) was significantly higher than mixed fed group (139.5 ± 37.59 mg/dl). At 9 mo, high density lipoprotein cholesterol (HDL-C) and triglycerides (TG) levels were significantly different in EBF group than MF group. The lipid profile of both group of babies was comparable at 1 y of age. The HDL-C: LDL-C ratio was significantly different between the two groups (higher in breastfed group) at 1 y.
The present study highlights differential lipid profile of exclusively breastfed infants and mixed fed infants.
比较足月、适于胎龄的纯母乳喂养和混合喂养婴儿6个月至1岁时的血脂情况。
这项前瞻性对照研究纳入了199名连续的足月健康婴儿；105名纯母乳喂养（EBF）婴儿和94名接受混合喂养（MF）的婴儿。这些儿童在6个月大时招募，随访至1岁。在招募时（6个月）、9个月和1岁时测定婴儿的血脂水平。使用SPSS软件进行统计分析。
纯母乳喂养组6个月时的平均总胆固醇（TC）（156.38±50.42mg/dl）显著高于混合喂养组（139.5±37.59mg/dl）。在9个月时，纯母乳喂养组的高密度脂蛋白胆固醇（HDL-C）和甘油三酯（TG）水平与混合喂养组有显著差异。两组婴儿在1岁时的血脂情况相当。两组在1岁时的HDL-C: LDL-C比值有显著差异（母乳喂养组更高）。
本研究突出了纯母乳喂养婴儿和混合喂养婴儿血脂情况的差异。
