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精油的抗癌活性:针对癌细胞中的蛋白质网络

Anticancer activity of essential oils: targeting of protein networks in cancer cells.

作者信息

Aras Aliye, Iqbal Muhammed Javed, Naqvi Syed Kamran-Ul-Hassan, Gercek Yusuf Can, Boztas Kadir, Gasparri Maria Luisa, Shatynska-Mytsyk Iryna, Fayyaz Sundas, Farooqi Ammad Ahmad

机构信息

Department of Botany, Faculty of Science, Istanbul University, Istanbul, Turkey E-mail :

出版信息

Asian Pac J Cancer Prev. 2014;15(19):8047-50. doi: 10.7314/apjcp.2014.15.19.8047.

Abstract

Cancer is a multifaceted and genomically complex disease and research over decades has gradually and sequentially shown that essential biological mechanisms including cell cycle arrest and apoptosis are deregulated. The benefits of essential oils from different plants have started to gain appreciation as evidenced by data obtained from cancer cell lines and xenografted mice. Encouraging results obtained from preclinical studies have attracted considerable attention and various phytochemicals have entered into clinical trials.

摘要

癌症是一种多方面且基因组复杂的疾病,数十年来的研究已逐步且相继表明,包括细胞周期停滞和细胞凋亡在内的基本生物学机制已失调。来自不同植物的精油的益处已开始得到认可,从癌细胞系和异种移植小鼠获得的数据就证明了这一点。临床前研究取得的令人鼓舞的结果已引起了相当大的关注,各种植物化学物质已进入临床试验阶段。

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