Dou Xiang Feng, Lyu Yan Ning, Jiang Yi, Lin Chang Ying, Tian Li Li, Wang Quan Yi, Yang Yu Song, Li Chao, Sun Yu Lan, Guan Zeng Zhi, Zhang Xiu Chun, Li Xin Yu
Institute for Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
State Key Laboratory for Infectious Diseases Prevention and Control, National Institute of Communicable Disease Control & Prevention, Chinese Center of Disease Control & Prevention, Beijing 102206, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou 310003, China.
Biomed Environ Sci. 2014 Oct;27(10):807-10. doi: 10.3967/bes2014.116.
A population-based case-control study was conducted to evaluate the relative factors in the environments, agricultural works, outdoor activities, and the effectiveness of Lyme borreliosis (LB)- associated personal protective measures in Beijing. Thirty-four cases and 272 controls were personally interviewed by well-trained interviewers. Venous blood samples were taken from each subject. Sowing or harvesting in summer (OR=2.571, 95% CI: 1.109-5.962), living in house with weeding in the yard (OR=2.247, 95% CI: 1.062-4.755), and residence at the plain area (OR=2.630, 95% CI: 1.050-6.588) were the independent relative factors for seropositive LB. Wearing long pants and clothes with cuffs was the only protective behavior against tick bite (OR=0.186, 95% CI: 0.041-0.846). The findings showed that local farmers were easily infected with LB and almost no protective measure was taken against LB infection. Infection with LB was easier in residents of plain regions. Pets raising and outdoor activities were not the risk factors for infection with LB. Further studies are needed to fully understand the risk of infection with LB in China.
开展了一项基于人群的病例对照研究，以评估北京地区环境、农业劳作、户外活动中的相关因素，以及莱姆病（LB）相关个人防护措施的有效性。由训练有素的访谈员对34例病例和272名对照进行个人访谈。采集了每位受试者的静脉血样本。夏季播种或收割（比值比[OR]=2.571，95%置信区间[CI]：1.109 - 5.962）、居住在院子里有除草作业的房屋（OR=2.247，95% CI：1.062 - 4.755）以及居住在平原地区（OR=2.630，95% CI：1.050 - 6.588）是血清学阳性莱姆病的独立相关因素。穿长裤和袖口有收口的衣服是预防蜱叮咬的唯一保护行为（OR=0.186，95% CI：0.041 - 0.846）。研究结果表明，当地农民易感染莱姆病，且几乎未采取针对莱姆病感染的防护措施。平原地区居民更容易感染莱姆病。饲养宠物和户外活动不是莱姆病感染的危险因素。需要进一步研究以全面了解中国莱姆病感染风险。
