Ma Xiang, Ding Ming-Jie, Zhao Xiu-Xia, Sun Jing, Yang Jin-Zhi, Han Yu-Ling
Department of Respiratory Diseases, Qilu Children′s Hospital of Shandong University, Jinan 250022, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2014 Oct;16(10):997-1000.
To explore the features of pulmonary dysfunction in children with Mycoplasma pneumoniae pneumonia (MPP) with different chest imaging findings.
The clinical data from 215 children with MPP were reviewed. These patients were grouped based on chest image findings (bronchopneumonia, n=125; lobar pneumonia, n=69; interstitial pneumonia, n=21). Lung function parameters including forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF), and the maximum mid-expiratory flow rate (MMEF 25%-75%) were compared between the groups.
In the acute stage, patients with bronchopneumonia had significantly lower PEF values (measured value and measured value/predicted value) than the other two groups of patients, children with lobar pneumonia had a significant lower MMEF 25%-75% than other patients, and children with interstitial pneumonia had a significantly lower FVC. All patients experienced an improvement in lung function parameters except FEV1 of the lobar pneumonia group in the recovery stage.
Various features of pulmonary dysfunction can be observed among children with MPP with different chest imaging findings. Patients with bronchopneumonia mainly exhibit large airway dysfunction. The ones with lobar pneumonia mainly suffer small airway dysfunction, and those with interstitial pneumonia demonstrate both airway obstruction and restrictive ventilatory dysfunction.
探讨不同胸部影像学表现的支原体肺炎(MPP)患儿肺功能障碍的特点。
回顾性分析215例MPP患儿的临床资料。根据胸部影像学表现将这些患儿分组(支气管肺炎组,n = 125;大叶性肺炎组,n = 69;间质性肺炎组,n = 21)。比较各组间的肺功能参数,包括第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、呼气峰值流速(PEF)和最大呼气中期流速(MMEF 25%-75%)。
急性期,支气管肺炎患儿的PEF值(实测值及实测值/预测值)显著低于其他两组患儿,大叶性肺炎患儿的MMEF 25%-75%显著低于其他患儿,间质性肺炎患儿的FVC显著降低。除大叶性肺炎组在恢复期的FEV1外,所有患儿的肺功能参数均有改善。
不同胸部影像学表现的MPP患儿可观察到各种肺功能障碍特点。支气管肺炎患儿主要表现为大气道功能障碍。大叶性肺炎患儿主要存在小气道功能障碍,间质性肺炎患儿则表现为气道阻塞和限制性通气功能障碍。