Department of Pediatrics, Funan County People's Hospital, Funan County, Fuyang City 236300, Anhui Province, China.
Contrast Media Mol Imaging. 2022 Apr 22;2022:1985531. doi: 10.1155/2022/1985531. eCollection 2022.
Mycoplasma (MP) is defined as a common cause of pulmonary infections and accounts for up to four over ten of pneumonia in children over age 5. This study was aimed to explore the diagnosis and prognosis of mycoplasma pneumonia (MPP) in children using high-resolution computed tomography (CT) (HRCT). 71 children hospitalized with MPP were undertaken as the research objects to observe the incidence rate, occurrence time, and duration of the clinical symptoms and pathological signs. The chest HRCT and pulmonary ventilation function (PVF) were examined in the acute phase, the second phase re-examination period, and the third phase re-examination period. Relevant indicators were statistically analyzed to determine the change rules of chest HRCT and PVF and correlation between the two. Clinically, the children with MPP suffered from fever, cough, and sore throat. In addition to the above symptoms, children with MPP had different degrees of PVF impairment. Compared with the group with normal HRCT results, the forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), peak expiratory flow (PEF), forced expiratory flow at 25% forced expiratory volume (FEF25), forced expiratory flow at 50% forced expiratory volume (FEF50), forced expiratory flow at 75% forced expiratory volume (FEF75), and maximum mid-expiratory flow (MMEF75/25) of children in bronchopneumonia group, segmental pneumonia group, and lobar pneumonia group were obviously reduced, showing statistically great differences ( < 0.05). Compared with the case in acute phase, the PVF indicators of children in the re-examination phases were much higher, with greatly statistical differences ( < 0.05). In children with MPP, both the large and small airways were affected, but the recovery of the small airways was slow. Pulmonary HRCT and PVF can be undertaken as important indicators to judge the severity and prognosis of MPP in school-age children.
支原体(MP)被定义为肺部感染的常见原因,占 5 岁以上儿童肺炎的十分之四以上。本研究旨在探讨高分辨率计算机断层扫描(HRCT)在儿童支原体肺炎(MPP)诊断和预后中的应用。对 71 例住院 MPP 患儿进行观察,观察临床症状和病理征象的发生率、出现时间和持续时间。在急性期、第二期复查期和第三期复查期进行胸部 HRCT 和肺通气功能(PVF)检查。对相关指标进行统计分析,确定胸部 HRCT 和 PVF 的变化规律及两者的相关性。临床上,MPP 患儿发热、咳嗽、咽痛。除上述症状外,MPP 患儿还存在不同程度的 PVF 损害。与 HRCT 结果正常组相比,支气管肺炎组、节段性肺炎组和大叶性肺炎组的患儿用力肺活量(FVC)、第 1 秒用力呼气量(FEV1)、呼气峰流速(PEF)、25%用力呼气量时的用力呼气流量(FEF25)、50%用力呼气量时的用力呼气流量(FEF50)、75%用力呼气量时的用力呼气流量(FEF75)和最大呼气中期流量(MMEF75/25)明显降低,差异有统计学意义( < 0.05)。与急性期相比,复查期患儿的 PVF 指标明显升高,差异有统计学意义( < 0.05)。MPP 患儿大、小气道均受累,但小气道恢复缓慢。肺部 HRCT 和 PVF 可作为判断学龄期儿童 MPP 严重程度和预后的重要指标。