Huang Y S
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1989 Dec;11(6):460-2.
Ginsenosides Rb1 and Rg1 were found to inhibit to some degree both VitC-NADPH and Fe2(+)-cysteine induced lipid peroxidation of rat liver and brain microsomes. However, the inhibitory effect of Rb1 and Rg1 was obvious in liver microsomes, especially in Vit C-NADPH induced lipid peroxidation of liver microsomes. Besides, Rb1 was shown to be more potent than Rg1 in inhibiting VitC-NADPH or Fe2(+)-cysteine induced lipid peroxidation. The inhibitory effect of Rb1 on VitC-NADPH induced lipid peroxidation was similar to that of VitE at the same concentration.
人参皂苷Rb1和Rg1在一定程度上可抑制维生素C - 烟酰胺腺嘌呤二核苷酸磷酸(VitC - NADPH)和Fe2(+) - 半胱氨酸诱导的大鼠肝脏和脑微粒体脂质过氧化。然而,Rb1和Rg1对肝脏微粒体的抑制作用明显,尤其是对VitC - NADPH诱导的肝脏微粒体脂质过氧化。此外,在抑制VitC - NADPH或Fe2(+) - 半胱氨酸诱导的脂质过氧化方面,Rb1比Rg1更有效。相同浓度下,Rb1对VitC - NADPH诱导的脂质过氧化的抑制作用与维生素E相似。