Bianchi Alberto, Mauri Michele, Bonetti Simone, Koynov Kaloian, Kappl Michael, Lieberwirth Ingo, Butt Hans-Jürgen, Simonutti Roberto
Department of Materials Science, University of Milan "Bicocca", via R. Cozzi 53, Milan, 20125, Italy.
Macromol Rapid Commun. 2014 Dec;35(23):1994-9. doi: 10.1002/marc.201400414. Epub 2014 Oct 27.
The hierarchical self-assembly of an amphiphilic block copolymer, poly(N,N-dimethylacrylamide)-block-polystyrene with a very short hydrophilic block (PDMA10 -b-PS62 ), in large granular nanoparticles is reported. While these nanoparticles are stable in water, their disaggregation can be induced either mechanically (i.e., by applying a force via the tip of the cantilever of an atomic force microscope (AFM)) or by partial hydrolysis of the acrylamide groups. AFM force spectroscopy images show the rupture of the particle as a combination of collapse and flow, while scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images of partly hydrolyzed nanoparticles provide a clear picture of the granular structure.
报道了一种两亲性嵌段共聚物聚（N，N-二甲基丙烯酰胺）-嵌段-聚苯乙烯（具有非常短的亲水性嵌段，即PDMA10-b-PS62）在大颗粒纳米粒子中的分级自组装。虽然这些纳米粒子在水中是稳定的，但它们的解聚可以通过机械方式（即通过原子力显微镜（AFM）的悬臂尖端施加力）或通过丙烯酰胺基团的部分水解来诱导。AFM力谱图像显示颗粒的破裂是塌陷和流动的组合，而部分水解的纳米粒子的扫描电子显微镜（SEM）和透射电子显微镜（TEM）图像则清晰地呈现出颗粒结构。
