J Oral Facial Pain Headache. 2014 Fall;28(4):322-30. doi: 10.11607/ofph.1277.
To assess whether trait anxiety as a person's general disposition to be anxious is a risk factor for temporomandibular disorder (TMD) pain.
A total of 320 adult TMD patients with at least one pain-related TMD diagnosis according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) were included in the study. Subjects from the general population without pain-related TMD were used as controls (n = 888). All study participants completed the State-Trait Anxiety Inventory (STAI). The association between the level of trait anxiety (STAI-Trait scores) and case-control status (patients diagnosed with pain-related TMD and controls) was analyzed using logistic regression analysis. Odds ratios (OR) with 95% confidence intervals (CI) were computed.
The level of trait anxiety was associated with the subject status (case vs control). A one-point increase in STAI-Trait sum scores (range: 20 to 80) was related to an increase of the odds for pain-related TMD by the factor 1.04 (CI: 1.02-1.05; P < .001). Severe trait anxiety (above the 90th percentile of general-population subjects) doubled the odds (OR: 2.05; CI: 1.42-2.98; P < .001). Analyses adjusted for age, gender, and level of education did not change the results.
Trait anxiety is significantly associated with diagnoses of TMD pain.
评估特质焦虑(一个人普遍的焦虑倾向)是否是颞下颌关节紊乱病(TMD)疼痛的危险因素。
本研究共纳入 320 名 TMD 患者,这些患者均至少有一项与疼痛相关的 TMD 诊断,符合颞下颌关节紊乱诊断与治疗研究(RDC/TMD)标准。选择无疼痛相关 TMD 的一般人群作为对照组(n=888)。所有研究参与者均完成状态-特质焦虑量表(STAI)。采用逻辑回归分析,分析特质焦虑水平(STAI-Trait 评分)与病例对照状态(诊断为疼痛相关 TMD 的患者和对照组)之间的相关性。计算比值比(OR)及其 95%置信区间(CI)。
特质焦虑水平与研究对象的状态(病例组与对照组)有关。STAI-Trait 总分增加 1 分(范围:20 至 80),与疼痛相关 TMD 的发生几率增加 1.04 倍(CI:1.02-1.05;P<0.001)。严重的特质焦虑(高于一般人群中 90%分位数的分数)使发生几率增加两倍(OR:2.05;CI:1.42-2.98;P<0.001)。调整年龄、性别和教育水平后,分析结果未发生改变。
特质焦虑与 TMD 疼痛的诊断显著相关。