哺乳与生物免疫抑制药物的使用。
Lactation and the use of biologic immunosuppressive medications.
机构信息
Saskatoon Co-op Pharmacy , Saskatoon, Saskatchewan, Canada .
出版信息
Breastfeed Med. 2014 Dec;9(10):543-6. doi: 10.1089/bfm.2014.0107.
Abstract
Biologic medications are effective therapeutic options for treating autoimmune diseases, but information on their safety in lactation is still scarce. Autoimmune conditions occur frequently in women of childbearing age, creating difficult decisions regarding optimizing maternal health and supporting breastfeeding. Available data, in addition to the favorable pharmacokinetic properties of biologics, suggest that these medications are compatible with breastfeeding. A review of the available evidence and information is presented, as well as recommendations on counseling the nursing mother and her healthcare team to make informed decisions about maternal and infant care.
摘要
生物制剂是治疗自身免疫性疾病的有效治疗选择，但关于其在哺乳期安全性的信息仍然很少。自身免疫性疾病在育龄妇女中很常见，这就需要在优化产妇健康和支持母乳喂养方面做出艰难的决策。除了生物制剂良好的药代动力学特性外，现有数据还表明这些药物与母乳喂养兼容。本文回顾了现有证据和信息，并就如何为哺乳期母亲及其医疗团队提供咨询建议以做出有关母婴护理的知情决策提出了建议。
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