Walters Arthur S, Frauscher Birgit, Allen Richard, Benes Heike, Chaudhuri K Ray, Garcia-Borreguero Diego, Lee Hochang B, Picchietti Daniel L, Trenkwalder Claudia, Martinez-Martin Pablo, Stebbins Glenn T, Schrag Anette
Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN.
Department of Neurology Medical University of Innsbruck, Austria.
J Clin Sleep Med. 2014 Dec 15;10(12):1351-7. doi: 10.5664/jcsm.4300.
Over the last decade therapeutic, pathogenetic, epidemiological and genetic research in restless legs syndrome/Willis-Ekbom Disease (RLS/WED) has required the development of specific quality of life scales and sleep scales. A Movement Disorder Society Task Force formally evaluated the quality of these scales.
A literature search retrieved 5 quality of life instruments specific to RLS. As per MDS protocol, each scale was evaluated by 3 criteria which included (a) use in RLS, (b) use by research or clinical groups other than the group that developed the scale, and (c) formal validation and adequate clinimetric properties. Scales were categorized as "Recommended" when all 3 criteria were met, "Suggested" when used for RLS but only one of the other criteria was met, and "Listed" when used in RLS but there was absence of the other two criteria. Details regarding the development, use and clinimetric properties of each instrument are summarized along with the recommendations of the Task Force.
The Restless Legs Syndrome Quality of Life Scale-Abetz (RLS-QOL-Abetz) is the only scale designated as Recommended for use in cross-sectional assessments and treatment-related changes in RLS quality of life. Daily diaries hold future promise for the evaluation of RLS symptoms without the need for retrospective recall. An important need is the development of pediatric RLS quality of life instruments.
在过去十年中，不安腿综合征/Willis-Ekbom病（RLS/WED）的治疗、发病机制、流行病学和遗传学研究需要开发特定的生活质量量表和睡眠量表。运动障碍协会特别工作组正式评估了这些量表的质量。
文献检索得到了5种针对RLS的生活质量工具。根据MDS方案，每个量表通过3项标准进行评估，包括（a）在RLS中的使用情况，（b）量表开发组以外的研究或临床组的使用情况，以及（c）正式验证和充分的临床测量特性。当所有3项标准都满足时，量表被归类为“推荐”；当用于RLS但仅满足其他标准之一时，归类为“建议”；当用于RLS但不满足其他两项标准时，归类为“列出”。每个工具的开发、使用和临床测量特性的详细信息以及特别工作组的建议都进行了总结。
不安腿综合征生活质量量表-Abetz（RLS-QOL-Abetz）是唯一被指定为推荐用于RLS生活质量横断面评估和治疗相关变化评估的量表。日常日记在评估RLS症状方面具有未来潜力，无需回顾性回忆。一个重要需求是开发儿科RLS生活质量工具。
