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具有可耐受毒副作用的细胞印迹抗菌仿生纳米材料。

Cell-imprinted antimicrobial bionanomaterials with tolerable toxic side effects.

机构信息

Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China; University of Chinese Academy of Sciences, Beijing, 100039, China.

出版信息

Small. 2015 Mar 18;11(11):1258-64. doi: 10.1002/smll.201402400. Epub 2014 Oct 27.

Abstract

Taking advantage of imprinting technology, artificial antibody-microbial imprinted Ag-TiO(2) materials are fabricated for microbial inactivation using a facile and green method. Due to the induced shape and size recognition elements, the artificial antibodies specifically recognize and kill target microbes under visible-light irradiation with minimal toxic side effects toward mammalian cells.

摘要

利用印迹技术,通过一种简便、绿色的方法制备了人工抗体-微生物印迹 Ag-TiO2 材料,用于微生物失活。由于诱导的形状和大小识别元件,人工抗体在可见光照射下特异性识别和杀死靶微生物,对哺乳动物细胞的毒性副作用最小。

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