Shacham Enbal, Önen Nur F, Donovan Michael F, Rosenburg Neal, Overton E Turner
Department of Behavioral Sciences and Health Education, College for Public Health and Social Justice, Saint Louis University, St Louis, MO, USA
Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
J Int Assoc Provid AIDS Care. 2016 Mar-Apr;15(2):126-30. doi: 10.1177/2325957414553846. Epub 2014 Oct 27.
As individuals with HIV infection are living longer, the management of psychiatric disorders has increasingly been incorporated into comprehensive care. Individuals were recruited from an outpatient HIV clinic to assess the prevalence and related associations of current psychiatric disorders and biomarkers. Of the 201 participants who completed the interviews, the median age was 43.5 years, and the majority was male and African American. Most were receiving HIV therapy and 78% of those had achieved virologic suppression. Prevalent psychiatric diagnoses included major depressive disorder, generalized anxiety, and agoraphobia. Alcohol and cocaine/crack abuse and dependence were common substance use disorders. Current receipt of HIV therapy was less common among those diagnosed with generalized anxiety disorder. Agoraphobia was the only disorder associated with unsuppressed viral load. Psychiatric and substance use disorders are highly prevalent among an urban HIV clinic population, although we identified few associations between psychiatric diagnoses and HIV diseases status.
随着感染艾滋病毒的个体寿命延长,精神障碍的管理越来越多地被纳入综合护理中。从一家门诊艾滋病毒诊所招募个体,以评估当前精神障碍和生物标志物的患病率及相关关联。在完成访谈的201名参与者中,中位年龄为43.5岁,大多数为男性和非裔美国人。大多数人正在接受艾滋病毒治疗,其中78%已实现病毒学抑制。常见的精神诊断包括重度抑郁症、广泛性焦虑症和广场恐惧症。酒精和可卡因/快克滥用及依赖是常见的物质使用障碍。在被诊断为广泛性焦虑症的患者中,目前接受艾滋病毒治疗的情况较少见。广场恐惧症是唯一与病毒载量未被抑制相关的障碍。精神和物质使用障碍在城市艾滋病毒诊所人群中非常普遍,尽管我们发现精神诊断与艾滋病毒疾病状态之间的关联很少。