综合瑜伽对HIV-1感染患者心理状态及CD4计数的影响：一项随机对照试验性研究
Effect of Integrated Yoga (IY) on psychological states and CD4 counts of HIV-1 infected patients: A randomized controlled pilot study.
作者信息
Naoroibam Rosy, Metri Kashinath G, Bhargav Hemant, Nagaratna R, Nagendra H R
机构信息
School of Yoga and Life Sciences, S-VYASA University, Bengaluru, Karnataka, India.
Holistic Health Center, S-VYASA University, Bengaluru, Karnataka, India.
出版信息
Int J Yoga. 2016 Jan-Jun;9(1):57-61. doi: 10.4103/0973-6131.171723.
BACKGROUND
Human immunodeficiency virus (HIV) infected individuals frequently suffer from anxiety and depression. Depression has been associated with rapid decline in CD4 counts and worsened treatment outcomes in HIV-infected patients. Yoga has been used to reduce psychopathology and improve immunity.
AIM
To study the effect of 1-month integrated yoga (IY) intervention on anxiety, depression, and CD4 counts in patients suffering from HIV-1 infection.
METHODS
Forty four HIV-1 infected individuals from two HIV rehabilitation centers of Manipur State of India were randomized into two groups: Yoga (n = 22; 12 males) and control (n = 22; 14 males). Yoga group received IY intervention, which included physical postures (asanas), breathing practices (pranayama), relaxation techniques, and meditation. IY sessions were given 60 min/day, 6 days a week for 1 month. Control group followed daily routine during this period. All patients were on anti-retroviral therapy (ART) and dosages were kept stable during the study. There was no significant difference in age, gender, education, CD4 counts, and ART status between the two groups. Hospital anxiety and depression scale was used to assess anxiety and depression, CD4 counts were measured by flow cytometry before and after intervention. Analysis of variance - repeated measures was applied to analyze the data using SPSS version 10.
RESULTS
Within group comparison showed a significant reduction in depression scores (F [1, 21] =4.19, P < 0.05) and non-significant reduction in anxiety scores along with non significant increment in CD4 counts in the yoga group. In the control group, there was a non-significant increase in anxiety and depression scores and reduction in CD4 counts. Between-group comparison revealed a significant reduction in depression scores (F [1, 21] =5.64, P < 0.05) and significant increase in CD4 counts (F [1, 21] =5.35, P < 0.05) in the yoga group as compared to the control.
CONCLUSION
One month practice of IY may reduce depression and improve immunity in HIV-1 infected adults.
背景
人类免疫缺陷病毒（HIV）感染者经常患有焦虑和抑郁。抑郁与HIV感染患者的CD4细胞计数快速下降及治疗效果恶化有关。瑜伽已被用于减轻精神病理学症状并提高免疫力。
目的
研究为期1个月的综合瑜伽（IY）干预对HIV-1感染患者焦虑、抑郁及CD4细胞计数的影响。
方法
来自印度曼尼普尔邦两个HIV康复中心的44名HIV-1感染者被随机分为两组：瑜伽组（n = 22；12名男性）和对照组（n = 22；14名男性）。瑜伽组接受IY干预，包括体式（体式法）、呼吸练习（调息法）、放松技巧和冥想。IY课程每天进行60分钟，每周6天，共1个月。在此期间，对照组遵循日常作息。所有患者均接受抗逆转录病毒治疗（ART），且在研究期间剂量保持稳定。两组在年龄、性别、教育程度、CD4细胞计数和ART状态方面无显著差异。采用医院焦虑抑郁量表评估焦虑和抑郁情况，干预前后通过流式细胞术测量CD4细胞计数。使用SPSS 10版软件应用方差分析 - 重复测量来分析数据。
结果
组内比较显示，瑜伽组的抑郁评分显著降低（F [1, 21] = 4.19，P < 0.05），焦虑评分无显著降低，CD4细胞计数无显著增加。在对照组中，焦虑和抑郁评分无显著增加，CD4细胞计数降低。组间比较显示，与对照组相比，瑜伽组的抑郁评分显著降低（F [1, 21] = 5.64，P < 0.05），CD4细胞计数显著增加（F [1, 21] = 5.35，P < 0.05）。
结论
为期1个月的IY练习可能会减轻HIV-1感染成年人的抑郁并提高免疫力。
Zotero 插件