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心血管磁共振在冠状动脉评估中的作用

Contribution of cardiovascular magnetic resonance in the evaluation of coronary arteries.

作者信息

Mavrogeni Sophie, Markousis-Mavrogenis George, Kolovou Genovefa

机构信息

Sophie Mavrogeni, George Markousis-Mavrogenis, Genovefa Kolovou, Onassis Cardiac Surgery Center, 17561 Athens, Greece.

出版信息

World J Cardiol. 2014 Oct 26;6(10):1060-6. doi: 10.4330/wjc.v6.i10.1060.

Abstract

Cardiovascular magnetic resonance (CMR) allows the nonradiating assessment of coronary arteries; to achieve better image quality cardiorespiratory artefacts should be corrected. Coronary MRA (CMRA) at the moment is indicated only for the detection of abnormal coronary origin, coronary artery ectasia and/or aneurysms (class I indication) and coronary bypass grafts (class II indication). CMRA utilisation for coronary artery disease is not yet part of clinical routine. However, the lack of radiation is of special value for the coronary artery evaluation in children and women. CMRA can assess the proximal part of coronary arteries in almost all cases. The best results have been observed in the evaluation of the left anterior descending and the right coronary artery, while the left circumflex, which is located far away from the coil elements, is frequently imaged with reduced quality, compared to the other two. Different studies detected an increase in wall thickness of the coronaries in patients with type I diabetes and abnormal renal function. Additionally, the non-contrast enhanced T1-weighed images detected the presence of thrombus in acute myocardial infarction. New techniques using delayed gadolinium enhanced imaging promise the direct visualization of inflamed plaques in the coronary arteries. The major advantage of CMR is the potential of an integrated protocol offering assessment of coronary artery anatomy, cardiac function, inflammation and stress perfusion-fibrosis in the same study, providing an individualized clinical profile of patients with heart disease.

摘要

心血管磁共振成像(CMR)可对冠状动脉进行无辐射评估;为获得更好的图像质量,应校正心肺伪影。目前,冠状动脉磁共振血管造影(CMRA)仅适用于检测冠状动脉起源异常、冠状动脉扩张和/或动脉瘤(I类适应证)以及冠状动脉旁路移植术(II类适应证)。CMRA用于冠状动脉疾病的诊断尚未成为临床常规操作。然而,无辐射这一特性对于儿童和女性的冠状动脉评估具有特殊价值。CMRA几乎在所有情况下都能评估冠状动脉近端。在评估左前降支和右冠状动脉时观察到了最佳结果,而左旋支远离线圈元件,与其他两支冠状动脉相比,其成像质量常常较低。不同研究发现,I型糖尿病和肾功能异常患者的冠状动脉壁厚度增加。此外,非对比增强T1加权图像可检测急性心肌梗死中血栓的存在。使用延迟钆增强成像的新技术有望直接显示冠状动脉内的炎症斑块。CMR的主要优势在于有可能在同一项研究中提供综合方案,对冠状动脉解剖结构、心脏功能、炎症和应激灌注纤维化进行评估,从而为心脏病患者提供个性化的临床资料。

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