利用H⁺/Ag⁺诱导的i-基序结构构建DNA逻辑门。

Construction of DNA logic gates utilizing a H+/Ag+ induced i-motif structure.

作者信息

Shi Yunhua, Sun Hongxia, Xiang Junfeng, Chen Hongbo, Yang Qianfan, Guan Aijiao, Li Qian, Yu Lijia, Tang Yalin

机构信息

National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry Chinese Academy of Sciences, Beijing, 100190, P. R. China.

出版信息

Chem Commun (Camb). 2014 Dec 18;50(97):15385-8. doi: 10.1039/c4cc06980c. Epub 2014 Oct 28.

DOI:10.1039/c4cc06980c

PMID:25349963

Abstract

A simple technology to construct diverse DNA logic gates (OR and INHIBIT) has been designed utilizing a H(+) and/or Ag(+) induced i-motif structure. The logic gates are easily controlled and also show a real time response towards inputs. The research provides a new insight for designing DNA logic gates using an i-motif DNA structure.

摘要

一种利用H(+)和/或Ag(+)诱导的i-基序结构构建多种DNA逻辑门（或门和抑制门）的简单技术已经被设计出来。这些逻辑门易于控制，并且对输入显示出实时响应。该研究为利用i-基序DNA结构设计DNA逻辑门提供了新的见解。