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一名长期持续非卧床腹膜透析(CAPD)患者的β2微球蛋白淀粉样变性

Beta-2 microglobulin amyloidosis in a patient on long-term continuous ambulatory peritoneal dialysis (CAPD).

作者信息

Colombi A, Wegmann W

机构信息

Renal Unit, Med. Dep. Kantonsspital, Lucerne, Switzerland.

出版信息

Perit Dial Int. 1989;9(4):321-4.

PMID:2535112
Abstract

A 61-year-old female patient with ESRD due to analgesic nephropathy and treated solely with CAPD for 81 months is described. During this period she developed peritonitis 4 times. She eventually died of acute pulmonary edema due to coronary heart disease. The autopsy showed an analgesic nephropathy with contracted kidneys, diffuse peritoneal fibrosis, and articular and periarticular amyloidosis of AB2m-type. This form of amyloidosis is well known after hemodialysis; it was, however, not observed heretofore after sole long-term CAPD.

摘要

本文描述了一名61岁女性患者,因止痛剂肾病导致终末期肾病,仅接受持续非卧床腹膜透析(CAPD)治疗81个月。在此期间,她发生了4次腹膜炎。她最终死于冠心病引起的急性肺水肿。尸检显示为止痛剂肾病,伴有肾脏萎缩、弥漫性腹膜纤维化以及AB2m型关节和关节周围淀粉样变性。这种淀粉样变性在血液透析后很常见;然而,此前在单纯长期CAPD治疗后尚未观察到。

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