Signer S, Cummings J L, Benson D F
Department of Psychiatry, Royal Ottawa Hospital, Canada.
J Neuropsychiatry Clin Neurosci. 1989 Winter;1(1):40-5. doi: 10.1176/jnp.1.1.40.
Sixty-one inpatients manifesting chronic aphasic syndromes were reviewed. Most aphasic patients with behavioral abnormalities sufficiently severe to require hospitalization had posterior hemispheric lesions and fluent disorders. Thirty-eight (62%) had fluent aphasia, eight (13%) had nonfluent aphasia, and 15 (25%) had anomic, global, or transcortical aphasic syndromes. Delusions were more common among patients with fluent aphasias (58%), whereas depression was the most common psychiatric disorder among patients with anterior lesions (63%). Elation occurred in 12 patients, 11 with posterior lesions and 1 with a nonlocalizing syndrome. Neuropsychiatric disturbances in patients with chronic aphasia syndromes correlate with the type of language disorder and with the location of the associated lesion.
对61例表现为慢性失语综合征的住院患者进行了回顾性研究。大多数行为异常严重到需要住院治疗的失语患者有大脑半球后部病变和流利性障碍。38例（62%）为流利性失语，8例（13%）为非流利性失语，15例（25%）为命名性、完全性或经皮质性失语综合征。妄想在流利性失语患者中更常见（58%），而抑郁是大脑半球前部病变患者中最常见的精神障碍（63%）。12例患者出现欣快，其中11例有大脑半球后部病变，1例有非定位性综合征。慢性失语综合征患者的神经精神障碍与语言障碍类型及相关病变的位置有关。
