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非膨胀性可充气阴茎假体圆柱体的胶囊收缩伴 S 形畸形:处理和预防策略。

Capsular contraction with s-shaped deformity of nonlength-expanding inflatable penile prosthesis cylinders: management and prevention strategies.

机构信息

El Camino Urology Medical Group Mountain View, CA, USA.

Regional Urology Shreveport, LA, USA.

出版信息

Sex Med. 2013 Dec;1(2):95-8. doi: 10.1002/sm2.14.

DOI:10.1002/sm2.14
PMID:25356293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4184503/
Abstract

INTRODUCTION

Capsular contraction (CC) occurring with inflatable penile prosthesis (IPP) reservoirs has been reported by urologists as a cause of autoinflation. The concept of CC occurring around IPP cylinders has not been studied.

AIMS

Herein we report a case of CC occurring with nonlength-expanding IPP cylinders, resulting in an S-shaped deformity.

MAIN OUTCOME MEASURES

We sought to report a novel cause of S-shaped deformity in patients after IPP surgery.

METHODS

We reviewed a recent clinical case and conducted a literature review on capsular scar formation in prosthetic surgery. We also conducted a literature review of the inflammatory cascade related with prosthetic surgery.

RESULTS

Capsular contracture of nonlength-expanding cylinders resulting in S-shaped deformity has not been previously reported. The role of certain inflammatory markers seems to play a common role of capsular contracture in the penis and other prosthetic implantation sites.

CONCLUSIONS

Capsular contractures around the cylinders of an IPP can cause deformity, even in patients who have appropriately sized, nonlength-expanding cylinders. A better understanding is needed regarding the mechanical properties of the tunica albuginea and the inflammatory cascade associated with penile implant surgery. This case represents an argument for early and aggressive postoperative inflation of the IPP. Future studies should evaluate the role of inflammation modulators as adjuvant therapy after IPP surgery. Karpman E and Henry G. Capsular contraction with S-shaped deformity of nonlength-expanding inflatable penile prosthesis cylinders: Management and prevention strategies. Sex Med 2013;1:95-98.

摘要

简介

泌尿科医生报告称,可充气阴茎假体(IPP)储液器的包膜挛缩(CC)是自动充气的原因。围绕 IPP 圆柱体发生 CC 的概念尚未得到研究。

目的

本文报告了一例非长度扩张型 IPP 圆柱体发生 CC 的病例,导致 S 形畸形。

主要观察指标

我们旨在报告 IPP 手术后患者 S 形畸形的新病因。

方法

我们回顾了最近的临床病例,并对假体手术中包膜瘢痕形成进行了文献复习。我们还对与假体手术相关的炎症级联反应进行了文献复习。

结果

非长度扩张型圆柱体的包膜挛缩导致 S 形畸形,以前没有报道过。某些炎症标志物的作用似乎在阴茎和其他假体植入部位的包膜挛缩中发挥共同作用。

结论

IPP 圆柱体周围的包膜挛缩可导致畸形,即使在患者具有适当大小、非长度扩张型圆柱体的情况下也是如此。需要更好地了解白膜的机械性能和与阴茎植入手术相关的炎症级联反应。该病例为 IPP 术后早期和积极的充气提供了依据。未来的研究应评估炎症调节剂作为 IPP 手术后辅助治疗的作用。Karpman E 和 Henry G. 非长度扩张型可充气阴茎假体圆柱体的包膜挛缩伴 S 形畸形:处理和预防策略。性医学 2013;1:95-98.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2493/4184503/b98ffe8c4da8/sm20001-0095-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2493/4184503/b98ffe8c4da8/sm20001-0095-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2493/4184503/b98ffe8c4da8/sm20001-0095-f1.jpg

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本文引用的文献

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Laparascopic capsulotomy to treat autoinflation of inflatable penile prostheses.腹腔镜下囊切开术治疗可充气阴茎假体自动充气。
J Sex Med. 2012 Apr;9(4):1212-5. doi: 10.1111/j.1743-6109.2011.02525.x. Epub 2011 Oct 24.
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Pentoxifylline attenuates transforming growth factor-β1-stimulated collagen deposition and elastogenesis in human tunica albuginea-derived fibroblasts part 1: impact on extracellular matrix.己酮可可碱可减轻转化生长因子-β1刺激的人白膜来源成纤维细胞胶原沉积和弹性蛋白生成 第 1 部分:对细胞外基质的影响。
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Capsular contractures: a systematic review.
囊状挛缩:系统评价。
Plast Reconstr Surg. 2009 Dec;124(6):1808-1819. doi: 10.1097/PRS.0b013e3181bf7f26.
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Prospective and long-term evaluation of erect penile length obtained with inflatable penile prosthesis to that induced by intracavernosal injection.对使用可膨胀阴茎假体获得的勃起阴茎长度与海绵体内注射诱导的勃起阴茎长度进行前瞻性长期评估。
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Penile length alterations following penile prosthesis surgery.阴茎假体手术后阴茎长度的改变。
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Upsizing of inflatable penile implant cylinders in patients with corporal fibrosis.阴茎海绵体纤维化患者可膨胀阴茎假体柱体的增大术
J Sex Med. 2006 Jul;3(4):736-742. doi: 10.1111/j.1743-6109.2006.00263.x.
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The mentor Alpha 1 penile prosthesis with reservoir lock-out valve: effective prevention of auto-inflation with improved capability for ectopic reservoir placement.带储液囊锁定阀的Mentor Alpha 1阴茎假体:有效预防自动充盈,提高了异位放置储液囊的能力。
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Periprosthetic breast capsules contain the fibrogenic cytokines TGF-beta1 and TGF-beta2, suggesting possible new treatment approaches.假体周围乳腺包膜含有促纤维化细胞因子转化生长因子-β1和转化生长因子-β2,提示可能有新的治疗方法。
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Penile curvatures and aneurysmal defects with the Ultrex penile prosthesis corrected with insertion of the AMS700CX.使用AMS700CX阴茎假体植入术矫正的阴茎弯曲和动脉瘤样缺损。
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Ultrex cylinders: problems with uncontrolled lengthening (the S-shaped deformity).Ultrax 圆柱:存在延长不受控制的问题(S 形畸形)。
J Urol. 1996 Jan;155(1):135-7. doi: 10.1016/s0022-5347(01)66571-6.