Salyer Stephanie J, Ellis Esther M, Salomon Corvil, Bron Christophe, Juin Stanley, Hemme Ryan R, Hunsperger Elizabeth, Jentes Emily S, Magloire Roc, Tomashek Kay M, Desormeaux Anne Marie, Muñoz-Jordán Jorge L, Etienne Lesly, Beltran Manuela, Sharp Tyler M, Moffett Daphne, Tappero Jordan, Margolis Harold S, Katz Mark A
Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America; Centers for Disease Control and Prevention, San Juan, Puerto Rico.
PLoS Negl Trop Dis. 2014 Oct 30;8(10):e3269. doi: 10.1371/journal.pntd.0003269. eCollection 2014 Oct.
In October 2012, the Haitian Ministry of Health and the US CDC were notified of 25 recent dengue cases, confirmed by rapid diagnostic tests (RDTs), among non-governmental organization (NGO) workers. We conducted a serosurvey among NGO workers in Léogane and Port-au-Prince to determine the extent of and risk factors for dengue virus infection. Of the total 776 staff from targeted NGOs in Léogane and Port-au-Prince, 173 (22%; 52 expatriates and 121 Haitians) participated. Anti-dengue virus (DENV) IgM antibody was detected in 8 (15%) expatriates and 9 (7%) Haitians, and DENV non-structural protein 1 in one expatriate. Anti-DENV IgG antibody was detected in 162 (94%) participants (79% of expatriates; 100% of Haitians), and confirmed by microneutralization testing as DENV-specific in 17/34 (50%) expatriates and 42/42 (100%) Haitians. Of 254 pupae collected from 68 containers, 65% were Aedes aegypti; 27% were Ae. albopictus. Few NGO workers reported undertaking mosquito-avoidance action. Our findings underscore the risk of dengue in expatriate workers in Haiti and Haitians themselves.
2012年10月，海地卫生部和美国疾病控制与预防中心收到通报，称非政府组织工作人员中有25例近期登革热病例经快速诊断检测（RDT）确诊。我们在莱奥甘和太子港的非政府组织工作人员中开展了一项血清学调查，以确定登革热病毒感染的程度和危险因素。在莱奥甘和太子港目标非政府组织的776名工作人员中，173人（22%；52名外籍人员和121名海地人）参与了调查。8名（15%）外籍人员和9名（7%）海地人检测到抗登革热病毒（DENV）IgM抗体，1名外籍人员检测到DENV非结构蛋白1。162名（94%）参与者检测到抗DENV IgG抗体（79%的外籍人员；100%的海地人），其中17/34名（50%）外籍人员和42/42名（100%）海地人的抗体经微量中和试验确认为DENV特异性抗体。从68个容器中收集的254只蛹中，65%为埃及伊蚊；27%为白纹伊蚊。很少有非政府组织工作人员报告采取了防蚊措施。我们的研究结果强调了海地外籍工作人员和海地人自身感染登革热的风险。
