Fu Yue, Zhang Quan, Zhang Jing, Zhang Yun Ting
Department of Radiology, Tianjin Medical University General Hospital, Tianjin, China.
Eur Neurol. 2015;73(1-2):13-9. doi: 10.1159/000366099. Epub 2014 Oct 29.
To compare the effects of active and passive movements on brain activation in patients with cerebral infarction using fMRI.
Twenty-four hemiplegic patients with cerebral infarction were evaluated using fMRI. All patients performed active and passive finger opposition movements. Patients were instructed to perform the finger opposition movement for the active movement task. For the passive movement task, the subject's fingers were moved by the examiner to perform the finger opposition movement. Statistical parametric mapping software was used for statistical analyses and to process all data.
In the affected hemisphere, sensorimotor cortex (SMC) activation intensity and range were significantly stronger during the passive movement of the affected fingers compared to the active movement of the affected fingers (p < 0.05). However, there were no significant differences between active and passive movements of unaffected fingers in SMC activation intensity and range in the unaffected hemisphere (p > 0.05). In addition, the passive movement activated many other regions of the brain. The brain regions activated by passive movements of the affected fingers tended to center toward the contralateral SMC.
Our findings suggest that passive movements induce cortical reorganization in patients with cerebral infarction. Therefore, passive movement is likely beneficial for motor function recovery in patients with cerebral infarction.
使用功能磁共振成像（fMRI）比较主动运动和被动运动对脑梗死患者脑激活的影响。
对24例脑梗死偏瘫患者进行fMRI评估。所有患者均进行主动和被动的手指对指运动。指导患者在主动运动任务中进行手指对指运动。对于被动运动任务，检查者移动受试者的手指以进行手指对指运动。使用统计参数映射软件进行统计分析并处理所有数据。
在患侧半球，与患侧手指的主动运动相比，患侧手指被动运动期间感觉运动皮层（SMC）的激活强度和范围明显更强（p < 0.05）。然而，在健侧半球，健侧手指的主动和被动运动在SMC激活强度和范围方面没有显著差异（p > 0.05）。此外，被动运动激活了大脑的许多其他区域。患侧手指被动运动激活的脑区倾向于向对侧SMC集中。
我们的研究结果表明，被动运动可诱导脑梗死患者的皮质重组。因此，被动运动可能有利于脑梗死患者的运动功能恢复。
