Horváth Tamás, Horváth Barnabás, Varga Zsuzsa, Liktor Bálint, Szabadka Hajnalka, Csákó László, Liktor Bálint
Department of Otolaryngology and Head and Neck Surgery, Bajcsy-Zsilinszky Hospital, Maglódi Street 89-91, Budapest, 1106, Hungary.
Department of Otolaryngology and Head and Neck Surgery, County Hospital, Oberwart, Austria.
Eur Arch Otorhinolaryngol. 2015 Nov;272(11):3469-74. doi: 10.1007/s00405-014-3367-x. Epub 2014 Oct 31.
Infections in the neck layers and spaces are potentially life-threatening diseases causing further complications, like mediastinitis, airway obstruction, or sepsis. Despite of the need for a conservative approach, they still regularly require surgical intervention. Records of 17 patients with severe neck infections that were treated by wide external incision and open wound management were retrospectively analyzed. The aim of the study was to clinically characterize these most serious neck infections. The most common presenting symptoms were neck pain and tense neck mass (94-94%) regularly with fever (65%), always accompanied by a marked elevation of C reactive protein level (average 192 uG/l). These findings were constant and very similar among both the deep neck infection and necrotizing fasciitis cases. More than half of the patients (53%) had at least one systemic co-morbidity. The parapharyngeal space was most commonly affected (83%), but extended disease involving more than two major neck regions was found in 13 cases (76%). Dental (29%) was the most common primary infection, followed by peritonsillar abscess (23%), Microbiological results showed a wide variety of corresponding bacteria. Mediastinitis was developed in three cases (18%), and airway obstruction requiring tracheostomy in two cases (12%). All the patients survived. Severe neck infections are a heterogenous group of diseases regarding to the primary site of infection, microbiology, localisation and host reaction. However, rapidly developed, painful, tense neck mass with a highly elevated CRP level should always alert for an extended or phlegmonous process in the layers or spaces of the neck.
颈部各层及间隙感染是潜在的危及生命的疾病,可引发纵隔炎、气道梗阻或败血症等进一步并发症。尽管需要采取保守治疗方法,但它们仍经常需要手术干预。对17例因广泛外部切口和开放伤口处理进行治疗的严重颈部感染患者的记录进行了回顾性分析。本研究的目的是对这些最严重的颈部感染进行临床特征描述。最常见的症状是颈部疼痛和颈部肿块紧张(均为94%),常伴有发热(65%),且始终伴有C反应蛋白水平显著升高(平均192μg/l)。这些表现对于深部颈部感染和坏死性筋膜炎病例均持续且非常相似。超过一半的患者(53%)至少有一种全身性合并症。咽旁间隙最常受累(83%),但13例(76%)发现病变扩展至两个以上主要颈部区域。牙源性感染(29%)是最常见的原发性感染,其次是扁桃体周围脓肿(23%)。微生物学结果显示有多种相应细菌。3例(18%)发生纵隔炎,2例(12%)因气道梗阻需要行气管切开术。所有患者均存活。严重颈部感染在感染的原发部位、微生物学、定位和宿主反应方面是一组异质性疾病。然而,迅速出现的、疼痛的、紧张的颈部肿块伴CRP水平高度升高应始终警惕颈部各层或间隙出现扩展或蜂窝织炎样病变。