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颈部深部感染

Deep neck infection.

作者信息

Vieira Francisco, Allen Shawn M, Stocks Rose Mary S, Thompson Jerome W

机构信息

Department of Otolaryngology - Head and Neck Surgery, University of Tennessee Health Science Center, 956 Court Avenue, Suite B224, Memphis, TN 38163, USA.

出版信息

Otolaryngol Clin North Am. 2008 Jun;41(3):459-83, vii. doi: 10.1016/j.otc.2008.01.002.

Abstract

Deep neck infections present significant morbidity and mortality, particularly when associated with predisposing factors that impair a functional immunologic response. Familiarity with deep neck spaces and fascial planes is critical, because these form the basis for the emergent nature of the disease process. Common and potentially life-threatening complications include airway obstruction, jugular vein thrombosis, descending mediastinitis, sepsis, acute respiratory distress syndrome, and disseminated intravascular coagulation. The most common primary sources of deep neck infection are odontogenic, tonsillar, salivary gland, foreign body, and malignancy. Microbiology typically reveals mixed bacterial flora, including anaerobic species, that can rapidly progress to a fulminating necrotizing fasciitis. The treatment cornerstone remains securing the airway, providing efficient drainage and appropriate antibiotics, and improving immunologic status. A prolonged hospital stay should be anticipated.

摘要

深部颈部感染具有较高的发病率和死亡率,尤其是与损害功能性免疫反应的易感因素相关时。熟悉深部颈部间隙和筋膜平面至关重要,因为这些构成了疾病进程紧急性的基础。常见且可能危及生命的并发症包括气道梗阻、颈静脉血栓形成、下行性纵隔炎、脓毒症、急性呼吸窘迫综合征和弥散性血管内凝血。深部颈部感染最常见的主要来源是牙源性、扁桃体、唾液腺、异物和恶性肿瘤。微生物学检查通常显示混合细菌菌群,包括厌氧菌,可迅速发展为暴发性坏死性筋膜炎。治疗的基石仍然是确保气道通畅、提供有效的引流和适当的抗生素,并改善免疫状态。预计患者需要较长时间住院。

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