Wamser-Nanney Rachel, Scheeringa Michael S, Weems Carl F
Department of Psychiatry & Behavioral Sciences, Tulane University School of Medicine and
Department of Psychiatry & Behavioral Sciences, Tulane University School of Medicine and.
J Pediatr Psychol. 2016 Jan-Feb;41(1):128-37. doi: 10.1093/jpepsy/jsu096. Epub 2014 Oct 30.
To investigate the incidence and correlates of early treatment response among youth receiving cognitive behavioral therapy (CBT) for posttraumatic stress disorder (PTSD).
56 youth who participated in a randomized controlled trial of CBT for PTSD and D-cycloserine were included. Youth with PTSD symptoms below clinical cutoff after Session 4 of a 12-session protocol were classified as early treatment responders (32% of parent reports, 44.6% of child reports). Pretreatment characteristics were examined in relation to responder status.
Lower levels of pretreatment PTSD, depression, and anxiety symptoms and fewer trauma types were related to child- and parent-reported responder status (d = .57, d = .52, respectively). Early treatment response was maintained at follow-up.
Pretreatment symptoms levels and number of traumas may play an important role in predicting early treatment response. Correlates of early treatment response may provide avenues for identifying youth who could benefit from abbreviated protocols.
调查接受创伤后应激障碍(PTSD)认知行为疗法(CBT)的青少年早期治疗反应的发生率及其相关因素。
纳入56名参与PTSD和D-环丝氨酸CBT随机对照试验的青少年。在一个为期12节疗程的第4节之后,PTSD症状低于临床临界值的青少年被归类为早期治疗反应者(家长报告的占32%,儿童报告的占44.6%)。研究了与反应者状态相关的治疗前特征。
治疗前较低水平的PTSD、抑郁和焦虑症状以及较少的创伤类型与儿童和家长报告的反应者状态相关(效应量分别为d = 0.57和d = 0.52)。早期治疗反应在随访中得以维持。
治疗前症状水平和创伤数量可能在预测早期治疗反应中起重要作用。早期治疗反应的相关因素可能为识别可从简化疗程中受益的青少年提供途径。