Nnadi Dc, Singh S, Ahmed Y, Siddique S, Bilal S
Department of Obstetrics and Gynecology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
Department of Pathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
Ann Med Health Sci Res. 2014 Sep;4(Suppl 3):S213-7. doi: 10.4103/2141-9248.141961.
The pattern of gynecological malignancies varies among nations and even within health institution in the same country. Understanding the histo-pathological pattern of these malignancies will help in the management of the patient.
The aim of the following study is to establish the frequency, histo-pathological features, and distribution of genital tract malignancies as seen in a tertiary health institution in North - western Nigeria.
A retrospective analysis of data from ward admissions and discharge records, surgical biopsy materials from the theater and the histopathology laboratory results of slides. The study was carried out at the Usmanu Dan-Fodiyo University Teaching Hospital Sokoto, Nigeria. Data were entered into a study proforma and analysis was through SPSS version 15 (Chicago IL) for windows. The results were expressed in simple percentages, tables and charts.
During the study period (2000-2009), there were 404 cases of gynecological malignancies recorded in the hospital. Cervical cancer was the most common gynecological malignancy 274/404 (69%), followed by choriocarcinoma 52/404 (13.1%), ovarian cancer 46/404 (11.4%) while the least common was vaginal cancer 1/404 (0.3%). The mean age of the cancers was 54 years (28.3). The mean age of incidence of all ovarian cancers was 52.5 years (SD ± 16.2). Epithelial ovarian tumors had a mean age incidence of 67 (12) years, while that of ovarian germ cell tumors was 18.5 (8) years. The incidence of cervical cancer showed a rising trend. Moderately differentiated squamous cell carcinoma was the most common histological variant of cervical carcinoma 170/252 (67.5%). Among the ovarian tumors, epithelial cancers were the most common 38/46 (82.6%), and were followed by the germ cell tumors 5/46 (10.9%). Dysgerminoma was the predominant ovarian germ cell tumour 4/5 (80%). There were 50 deaths from these cancers in our hospital.
Cervical cancer is the most common gynecological malignancy in our centerand it was followed by Choriocarcinoma. Efforts to reduce the cancer burden should focus on heath education of the masses, national organized screening especially for cervical cancer and establishing regional centers for monitoring and evaluation of these programs.
妇科恶性肿瘤的模式在不同国家甚至在同一国家的卫生机构内部都有所不同。了解这些恶性肿瘤的组织病理学模式将有助于患者的管理。
以下研究的目的是确定在尼日利亚西北部一家三级卫生机构中所见的生殖道恶性肿瘤的发生率、组织病理学特征及分布情况。
对病房入院和出院记录、手术室手术活检材料以及组织病理学实验室玻片结果的数据进行回顾性分析。该研究在尼日利亚索科托的乌斯曼努·丹福迪奥大学教学医院开展。数据录入研究表格，通过适用于Windows系统的SPSS 15版（伊利诺伊州芝加哥）进行分析。结果以简单百分比、表格和图表形式呈现。
在研究期间（2000 - 2009年），该医院记录了404例妇科恶性肿瘤病例。宫颈癌是最常见的妇科恶性肿瘤，274/404（69%），其次是绒毛膜癌52/404（13.1%），卵巢癌46/404（11.4%），而最不常见的是阴道癌1/404（0.3%）。这些癌症患者的平均年龄为54岁（标准差±28.3）。所有卵巢癌的平均发病年龄为52.5岁（标准差±16.2）。上皮性卵巢肿瘤的平均发病年龄为67（12）岁，而卵巢生殖细胞肿瘤的平均发病年龄为18.5（8）岁。宫颈癌的发病率呈上升趋势。中分化鳞状细胞癌是宫颈癌最常见的组织学类型，170/252（67.5%）。在卵巢肿瘤中，上皮性癌最为常见，38/46（82.6%），其次是生殖细胞肿瘤5/46（10.9%）。无性细胞瘤是主要的卵巢生殖细胞肿瘤，4/5（80%）。我院有50例患者死于这些癌症。
在我们中心，宫颈癌是最常见的妇科恶性肿瘤，其次是绒毛膜癌。减轻癌症负担的努力应集中在对大众的健康教育、全国性有组织的筛查，尤其是宫颈癌筛查，以及建立这些项目的区域监测和评估中心。
