Moncada Salvador, Coaker Hannah
Future Med Chem. 2014 Sep;6(13):1481-3. doi: 10.4155/fmc.14.110.
Salvador Moncada studied medicine at the University of El Salvador (El Salvador) before coming to the UK in 1971 to work on a PhD with Professor John Vane at the Institute of Basic Medical Sciences, Royal College of Surgeons (UK). After a short period of research at the University of Honduras (Honduras), he joined the Wellcome Research Laboratories (UK) where he became Head of the Department of Prostaglandin Research and later, Director of Research. He returned to academic life in 1996 as founder and director of the Wolfson Institute for Biomedical Research at University College London (UK). Moncada played a role in the discovery of the mechanism of action of aspirin-like drugs and later led the teams which discover prostacyclin and identified nitric oxide as a biological mediator. In his role as a Director of Research of the Wellcome Laboratories, he oversaw the discovery and development of medicines for epilepsy, migraine, malaria and cancer. Currently, he is working on the regulation of cell proliferation as Director of the Institute of Cancer Sciences at the University of Manchester (UK). Moncada has won numerous awards from the international scientific community and in 2010, he received a knighthood from Her Majesty Queen Elizabeth II for his services to science.
萨尔瓦多·蒙卡达曾在萨尔瓦多大学学习医学，之后于1971年来到英国，在皇家外科医学院基础医学科学研究所与约翰·瓦恩教授一起攻读博士学位。在洪都拉斯大学进行了短期研究后，他加入了惠康研究实验室，在那里他成为前列腺素研究部主任，后来又担任研究主任。1996年，他回到学术界，成为英国伦敦大学学院沃尔夫森生物医学研究所的创始人兼所长。蒙卡达参与了阿司匹林类药物作用机制的发现，后来带领团队发现了前列环素，并确定一氧化氮为一种生物介质。在担任惠康实验室研究主任期间，他监督了用于治疗癫痫、偏头痛、疟疾和癌症的药物的发现和开发。目前，他作为英国曼彻斯特大学癌症科学研究所所长，致力于细胞增殖的调控研究。蒙卡达获得了国际科学界的众多奖项，并于2010年因对科学的贡献被女王伊丽莎白二世授予爵士头衔。
