Department of Nuclear Medicine and Centre for PET, Austin Health, Melbourne, 145 Studley Road, Heidelberg, Vic 3084, Australia.
The Florey Institute for Neuroscience and Mental Health, University of Melbourne, Genetics Lane, Royal Parade, Melbourne, Vic 3010, Australia.
Nat Rev Neurol. 2014 Dec;10(12):678-9. doi: 10.1038/nrneurol.2014.214. Epub 2014 Nov 4.
The knowledge of imaging and fluid biomarkers gained from longitudinal observational studies of Alzheimer disease has recently been translated to a cross-sectional study of randomly selected, cognitively unimpaired elderly individuals. This is the first time that a two-feature biomarker classification system has been applied to a population-based cohort.
从阿尔茨海默病的纵向观察研究中获得的影像学和液体生物标志物知识最近已被转化为对随机选择的认知正常老年人进行的横断面研究。这是首次将双特征生物标志物分类系统应用于基于人群的队列。
