Wang Xiang-qing, Lang Sen-yang, He Mian-wang, Zhang Xu, Zhu Fei, Dai Wei, Shi Xiao-Bing, Wan Min, Ma Yun-feng, Chen Ya-nan, Yu Sheng-yuan
Department of Neurology, Chinese PLA General Hospital, Fuxing Road 28, Haidian District, Beijing 100853, P,R, China.
J Headache Pain. 2014 Nov 4;15(1):70. doi: 10.1186/1129-2377-15-70.
To examine the association between headaches and epilepsy.
Consecutive adult epileptic patients who went to the outpatient clinic of the Epilepsy Center of PLA General Hospital between February 01, 2012, and May 10, 2013, were recruited into this study. A total of 1109 patients with epilepsy completed a questionnaire regarding headaches.
Overall, 60.1% of the patients (male: 57.2%; female: 63.8%) reported headaches within the last year. The age-weighted prevalence of interictal migraine was 11.7% (male 8.9%, female 15.3%), which is higher than that reported in a large population-based study (8.5%, male 5.4%, female 11.6%) using the same screening questions. The prevalence of postictal headaches was 34.1% (males 32.7%, females 35.2%), and the presence of preictal headaches was 4.5% (males 4.3%, females 5.2%). The prevalence of headache yesterday in the general population was 4.8% (male 3.0%, female 6.6%). Thus, the prevalence of headaches, including migraine, is higher in epileptic patients in China.
The high prevalence of postictal headaches confirms the frequent triggering of a headache by a seizure. A much lower frequency of preictal headaches, a condition in which the real triggering effect of the headache on the seizure might be difficult to prove.
探讨头痛与癫痫之间的关联。
选取2012年2月1日至2013年5月10日期间前往中国人民解放军总医院癫痫中心门诊就诊的成年癫痫患者作为研究对象。共有1109例癫痫患者完成了关于头痛的问卷调查。
总体而言，60.1%的患者（男性：57.2%；女性：63.8%）报告在过去一年中有头痛症状。发作间期偏头痛的年龄加权患病率为11.7%（男性8.9%，女性15.3%），高于一项基于大规模人群的研究（8.5%，男性5.4%，女性11.6%）使用相同筛查问题所报告的患病率。发作后头痛的患病率为34.1%（男性32.7%，女性35.2%），发作前头痛的患病率为4.5%（男性4.3%，女性5.2%）。普通人群中昨日头痛的患病率为4.8%（男性3.0%，女性6.6%）。因此，在中国癫痫患者中，包括偏头痛在内的头痛患病率较高。
发作后头痛的高患病率证实了癫痫发作频繁引发头痛。发作前头痛的发生率要低得多，而在这种情况下，头痛对癫痫发作的真正触发作用可能难以证实。
